Staff Profile
Dr Nicole Kattner
Research Associate
- Email: [email protected]
- Address: Translational and Clinical Research Institute
4th Floor William Leech Building
Medical School
Newcastle University
Framlington Place
NE2 4HH
Newcastle upon Tyne
Background
Qualifications
PhD Medical Science, Newcastle University, UK (2020)
MRes Medical Science, Newcastle University, UK (2016)
MSc Technical Biology, University of Stuttgart, Germany (2015)
BSc Technical Biology, University of Stuttgart, Germany (2013)
Research
During my PhD project titled 'Microenvironmental characterization of isolated islets and their endogenous niche towards bioengineering a microtissue for beta-cell replacement therapy' I investigated the impact of the isolation process on the islet of Langerhans and their microenvironment and explored different tissue engineering approaches to improve viability, function and morphology of these. Currently I am working on a project funded by the CF Trust investigating the impact of cystic fibrosis on islets and in more detail I am interested how the fibrotic environment of cystic fibrosis combined with the impaired function of CFTR impact on islet differentiation status and function.
Teaching
I am co-supervising BSc, MRes and PhD students.
Publications
- Al-Selwi Y, Shaw JAM, Kattner N. Understanding the Pancreatic Islet Microenvironment in Cystic Fibrosis and the Extrinsic Pathways Leading to Cystic Fibrosis Related Diabetes. Clinical Medicine Insights: Endocrinology and Diabetes 2021, 14, 1-7.