Staff Profile

Introduction

I provide the clinical lead for the day to day running of the Children's Bone Marrow Transplant unit in the Great North Children's Hospital.

Background

Started on the Children's BMT unit in November 1999 after working in the Democratic Republic of Congo.

Became an Associate Specialist in August 2004. Appointed as Consultant Paediatrician in HSCT 2014.

Roles and Responsibilities

Provide the clinical lead for the daily running of the Children's BMT unit.

Development of the longterm follow up programme.

Extensive involvement in clinical research for children with Primary Immunodeficiency undergoing HSCT.

Qualifications

MB ChB, FRCPCH

Memberships

UK Paediatric HSCT group

Inborn Errors of metabolism EBMT working party

Research Interests

New conditioning regimens for transplanting children with Primary Immunodeficiency.
Longterm follow up of patients with PID post Haematopoietic stem cell transplantation.

Current Work

Joint experience Newcastle/Great Ormond Street Hospital of using treosulfan-based conditioning regimens.
Haploidentical transplantation for PID using CD3 TCR alpha/beta/CD19 depletion.

Future Research

Longterm follow up studies.

Research Roles

PI in Newcastle for UKPIN national database for Primary Immunodeficiency disorders in children with electronic transfer of data to the European Society of Immunodeficiency (ESID) Patient and Research registry.

PI in Newcastle for Evaluation of Treosulfan pharmacokinetics in children undergoing allogeneic haematopoietic stem cell transplantation.

• Tholouli E, Sturgess K, Dickinson RE, Gennery A, Cant AJ, Jackson G, Lordan J, Hambleton S, Slatter MA, Bigley V, Collin M. In vivo T-depleted reduced intensity transplantation for GATA2-related immune dysfunction. Blood 2018, 131(12), 1383-1387.
• Altmann T, Slack J, Slatter MA, O'Brien C, Cant A, Thomas M, Brodlie M, Annavarapu S, Gennery AR. Endothelial cell damage in idiopathic pneumonia syndrome. Bone Marrow Transplantation 2018, 53(4), 515-518.
• Slatter MA, Gennery AR. Hematopoietic cell transplantation in primary immunodeficiency–conventional and emerging indications. Expert Review of Clinical Immunology 2018, 14(2), 103-114.
• Nademi Z, Wynn RF, Slatter M, Hughes SM, Bonney D, Qasim W, Latour S, Truck J, Patel S, Abinun M, Flood T, Hambleton S, Cant AJ, Gennery AR, Arkwright PD. Hematopoietic stem cell transplantation for cytidine triphosphate synthase 1 (CTPS1) deficiency. Bone Marrow Transplantation 2019, 54(1), 130-133.
• Leiding JW, Okada S, Hagin D, Abinun M, Shcherbina A, Balashov DN, Kim VHD, Ovadia A, Guthery SL, Pulsipher M, Lilic D, Devlin LA, Christie S, Depner M, Fuchs S, van Royen-Kerkhof A, Lindemans C, Petrovic A, Sullivan KE, Bunin N, Kilic SS, Arpaci F, Calle-Martin ODL, Martinez-Martinez L, Aldave JC, Kobayashi M, Ohkawa T, Imai K, Iguchi A, Roifman CM, Gennery AR, Slatter M, Ochs HD, Morio T, Torgerson TR. Hematopoietic stem cell transplantation in patients with gain-of-function signal transducer and activator of transcription 1 mutations. Journal of Allergy and Clinical Immunology 2018, 141(2), 704-717.e5.
• Barzaghi F, Amaya Hernandez LC, Neven B, Ricci S, Kucuk ZY, Bleesing JJ, Nademi Z, Slatter MA, Ulloa ER, Shcherbina A, Roppelt A, Worth A, Silva J, Aiuti A, Murguia-Favela L, Speckmann C, Carneiro-Sampaio M, Fernandes JF, Baris S, Ozen A, Karakoc-Aydiner E, Kiykim A, Schulz A, Steinmann S, Notarangelo LD, Gambineri E, Lionetti P, Shearer WT, Forbes LR, Martinez C, Moshous D, Blanche S, Fisher A, Ruemmele FM, Tissandier C, Ouachee-Chardin M, Rieux-Laucat F, Cavazzana M, Qasim W, Lucarelli B, Albert MH, Kobayashi I, Alonso L, Diaz De Heredia C, Kanegane H, Lawitschka A, Seo JJ, Gonzalez-Vicent M, Diaz MA, Goyal RK, Sauer MG, Yesilipek A, Kim M, Yilmaz-Demirdag Y, Bhatia M, Khlevner J, Richmond Padilla EJ, Martino S, Montin D, Neth O, Molinos-Quintana A, Valverde-Fernandez J, Broides A, Pinsk V, Ballauf A, Haerynck F, Bordon V, Dhooge C, Garcia-Lloret ML, Bredius RG, Kalwak K, Haddad E, Seidel MG, Duckers G, Pai S-Y, Dvorak CC, Ehl S, Locatelli F, Goldman F, Gennery AR, Cowan MJ, Roncarolo M-G, Bacchetta R. Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study. Journal of Allergy and Clinical Immunology 2018, 141(3), 1036-1049.e5.
• Ip W, Silva JMF, Gaspar H, Mitra A, Patel S, Rao K, Chiesa R, Amrolia P, Gilmour K, Ahsan G, Slatter M, Gennery AR, Wynn RF, Veys P, Qasim W. Multicenter phase 1/2 application of adenovirus-specific T cells in high-risk pediatric patients after allogeneic stem cell transplantation. Cytotherapy 2018, 20(6), 830-838.
• Unni MNM, Elfeky R, Rao K, Nademi Z, Chiesa R, Amrolia P, Skinner R, Slater O, Worth A, Flood T, Abinun M, Hambleton S, Qasim W, Gaspar HB, Cant AJ, Gennery AR, Veys P, Slatter MA. Non-posttransplant lymphoproliferative disorder malignancy after hematopoietic stem cell transplantation in patients with primary immunodeficiency: UK experience. Journal of Allergy and Clinical Immunology 2018, 141(6), 2319-2321.e1.
• Slack J, Albert MH, Balashov D, Belohradsky BH, Bertaina A, Bleesing J, Booth C, Buechner J, Buckley RH, Ouachee-Chardin M, Deripapa E, Drabko K, Eapen M, Feuchtinger T, Finocchi A, Gaspar HB, Ghosh S, Gillio A, Gonzalez-Granado LI, Grunebaum E, Gungor T, Heilmann C, Helminen M, Higuchi K, Imai K, Kalwak K, Kanazawa N, Karasu G, Kucuk ZY, Laberko A, Lange A, Mahlaoui N, Meisel R, Moshous D, Muramatsu H, Parikh S, Pasic S, Schmid I, Schuetz C, Schulz A, Schultz KR, Shaw PJ, Slatter MA, Sykora K-W, Tamura S, Taskinen M, Wawer A, Wolska-Kusnierz B, Cowan MJ, Fischer A, Gennery AR. Outcome of hematopoietic cell transplantation for DNA double-strand break repair disorders. Journal of Allergy and Clinical Immunology 2018, 141(1), 322-328.e10.
• Schwab C, Gabrysch A, Olbrich P, Patiño V, Warnatz K, Wolff D, Hoshino A, Kobayashi M, Imai K, Takagi M, Dybedal I, Haddock JA, Sansom D, Lucena JM, Seidl M, SchmittGräff A, Reiser V, Emmerich F, Frede N, Bulashevska A, Salzer U, Schubert D, Hayakawa S, Okada S, Kanariou M, Kucuk ZY, Chapdelaine H, Petruzelkova L, Sumnik Z, Sediva A, Slatter M, Arkwright PD, Cant A, Lorenz H-M, Giese T, Lougaris V, Plebani A, Price C, Sullivan KE, Moutschen M, Litzman J, Freiberger T, vandeVeerdonk FL, Recher M, Albert MH, Hauck F, Seneviratne S, Schmid JP, Kolios A, Unglik G, Klemann C, Speckmann C, Ehl S, Leichtner A, Blumberg R, Franke A, Snapper S, Zeissig S, Cunningham-Rundles C, Giulino-Roth L, Elemento O, Dückers G, Niehues T, Fronkova E, Kanderová V, Platt CD, Chou J, Chatila T, Geha R, McDermott E, Bunn S, Kurzai M, Schulz A, Alsina L, Casals F, Deyà-Martinez A, Hambleton S, Kanegane H, Taskén K, Neth O, Grimbacher B. Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects. Journal of Allergy and Clinical Immunology 2018, 142(6), 1932-1946.
• Shah RM, Elfeky R, Nademi Z, Qasim W, Amrolia P, Chiesa R, Rao K, Lucchini G, Silva JMF, Worth A, Barge D, Ryan D, Conn J, Cant AJ, Skinner R, Abd Hamid IJ, Flood T, Abinun M, Hambleton S, Gennery AR, Veys P, Slatter M. T-cell receptor αβ+ and CD19+ cell-depleted haploidentical and mismatched hematopoietic stem cell transplantation in primary immune deficiency. Journal of Allergy and Clinical Immunology 2018, 141(4), 1417-1426.e1.
• Shillitoe B, Bangs C, Guzman D, Gennery AR, Longhurst HJ, Slatter M, Edgar DM, Thomas M, Worth A, Huissoon A, Arkwright PD, Jolles S, Bourne H, Alachkar H, Savic S, Kumararatne DS, Patel S, Baxendale H, Noorani S, Yong PFK, Waruiru C, Pavaladurai V, Kelleher P, Herriot R, Bernatonienne J, Bhole M, Steele C, Hayman G, Richter A, Gompels M, Chopra C, Garcez T, Buckland M. The United Kingdom Primary Immune Deficiency (UKPID) registry 2012 to 2017. Clinical and Experimental Immunology 2018, 192(3), 284-291.
• Flinn AM, Roberts CF, Slatter MA, Skinner R, Robson H, Lawrence J, Guest J, Gennery AR. Thymopoiesis following HSCT; a retrospective review comparing interventions for aGVHD in a pediatric cohort. Clinical Immunology 2018, 193, 33-37.
• Slatter MA, Rao K, Abd Hamid IJ, Nademi Z, Chiesa R, Elfeky R, Pearce MS, Amrolia P, Worth A, Flood T, Abinun M, Hambleton S, Qasim W, Gaspar HB, Cant AJ, Gennery AR, Veys P. Treosulfan and Fludarabine Conditioning for Hematopoietic Stem Cell Transplantation in Children with Primary Immunodeficiency: UK Experience. Biology of Blood and Marrow Transplantation 2018, 24(3), 529-536.
• Slatter MA, Gennery AR. Approaches to the removal of T-lymphocytes to minimize graft-versus-host disease in patients with primary immunodeficiencies who do not have a matched sibling donor. Current Opinion in Allergy and Clinical Immunology 2017, 17(6), 414-420.
• Heimall J, Puck J, Buckley R, Fleisher TA, Gennery AR, Neven B, Slatter M, Haddad E, Notarangelo LD, Baker KS, Dietz AC, Duncan C, Pulsipher MA, Cowan MJ. Current Knowledge and Priorities for Future Research in Late Effects after Hematopoietic Stem Cell Transplantation (HCT) for Severe Combined Immunodeficiency Patients: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric HCT. Biology of Blood and Marrow Transplantation 2017, 23(3), 379-387.
• Duncan CJA, Dinnigan E, Theobald R, Grainger A, Skelton AJ, Hussain R, Willet JDP, Swan DJ, Coxhead J, Thomas MF, Thomas J, Zamvar V, Slatter MA, Cant AJ, Engelhardt KR, Hambleton S. Early-onset autoimmune disease due to a heterozygous loss-of-function mutation in TNFAIP3 (A20). Annals of the Rheumatic Diseases 2018, 77(5), 783-786.
• Palagano E, Slatter MA, Uva P, Menale C, Villa A, Abinun M, Sobacchi C. Hematopoietic stem cell transplantation corrects osteopetrosis in a child carrying a novel homozygous mutation in the FERMT3 gene. Bone 2017, 97, 126-129.
• Engelhardt KR, Xu Y, Grainger A, Germani Batacchi MGC, Swan DJ, Willet JDP, Abd Hamid IJ, Agyeman P, Barge D, Bibi S, Jenkins L, Flood TJ, Abinun M, Slatter MA, Gennery AR, Cant AJ, Santibanez Koref M, Gilmour K, Hambleton S. Identification of Heterozygous Single- and Multi-exon Deletions in IL7R by Whole Exome Sequencing. Journal of Clinical Immunology 2017, 37(1), 42-50.
• Yeates L, Slatter MA, Gennery AR. Infusion of sibling marrow in a patient with Purine nucleoside phosphorylase deficiency leads to split mixed donor chimerism and normal immunity. Frontiers in Pediatrics 2017, 5, 143.
• Heimall J, Buckley RH, Puck J, Fleisher TA, Gennery AR, Haddad E, Neven B, Slatter M, Skinner R, Baker KS, Dietz AC, Duncan C, Griffith LM, Notarangelo L, Pulsipher MA, Cowan MJ. Recommendations for Screening and Management of Late Effects in Patients with Severe Combined Immunodeficiency after Allogenic Hematopoietic Cell Transplantation: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric HCT. Biology of Blood and Marrow Transplantation 2017, 23(8), 1229-1240.
• Hoenig M, Lagresle-Peyrou C, Pannicke U, Notarangelo LD, Porta F, Gennery AR, Slatter M, Cowan MJ, Stepensky P, Al-Mousa H, Al-Zahrani D, Pai S-Y, Al Herz W, Gaspar HB, Veys P, Oshima K, Imai K, Yabe H, Noroski LM, Wulffraat NM, Sykora K-W, Soler-Palacin P, Muramatsu H, Al Hilali M, Moshous D, Debatin K-M, Schuetz C, Jacobsen E-M, Schulz AS, Schwarz K, Fischer A, Friedrich W, Cavazzana M. Reticular dysgenesis: International survey on clinical presentation, transplantation, and outcome. Blood 2017, 129(21), 2928-2938.
• Yeates L, Slatter MA, Bonanomi S, Lim FLWI, Ong SY, Dalissier A, Barberi W, Shulz A, Duval M, Heilmann C, Willekens A, Hwang WHY, Uderzo C, Bader P, Gennery AR. Use of defibrotide to treat transplant-associated thrombotic microangiopathy: a retrospective study of the Paediatric Diseases and Inborn Errors Working Parties of the European Society of Blood and Marrow Transplantation. Bone Marrow Transplantation 2017, 52, 762-764.
• Flinn A, Slatter M, Skinner R, Robson H, Cooper J, Guest J, Gennery A. A Retrospective Review of a Cohort of Paediatric Patients Treated with ECP for the Management of GVHD. In: 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation. 2016, Valencia, Spain: Nature Publishing Group.
• Abd Hamid IJ, Slatter M, Pearce MS, Gennery AR. A single centre cohort report of long term clinical outcome of severe combined immunodeficiency following haematopoietic stem cell transplantation. In: 2016 CIS Annual Meeting: Immune Deficiency & Dysregulation North American Conference. 2016, Boston, Massachusetts, USA: Springer US.
• Abd Hamid IJ, Slatter M, Pearce MS, Gennery A. A single centre cohort report of long term clinical outcome of severe combined immunodeficiency following haematopoietic stem cell transplantation. In: 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation. 2016, Valencia, Spain: Nature Publishing Group.
• Naik S, Nicholas SK, Martinez CA, Leen AM, Hanley PJ, Gottschalk SM, Rooney CM, Hanson IC, Krance RA, Shpall EJ, Cruz CR, Amrolia P, Lucchini G, Bunin N, Heimall J, Klein OR, Gennery AR, Slatter MA, Vickers MA, Orange JS, Heslop HE, Bollard CM, Keller MD. Adoptive immunotherapy for primary immunodeficiency disorders with virus-specific T lymphocytes. Journal of Allergy and Clinical Immunology 2016, 137(5), 1498-1505.e1.
• Bartelink IH, Lalmohamed A, van Reij EML, Dvorak CC, Savic RM, Zwaveling J, Bredius RGM, Egberts ACG, Bierings M, Kletzel M, Shaw PJ, Nath CE, Hempel G, Ansari M, Krajinovic M, Theoret Y, Duval M, Keizer RJ, Bittencourt H, Hassan M, Gungor T, Wynn RF, Veys P, Cuvelier GDE, Marktel S, Chiesa R, Cowan MJ, Slatter MA, Stricherz MK, Jennissen C, Long-Boyle JR, Boelens JJ. Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis. Lancet Haematology 2016, 3(11), e526-e536.
• Bartelink IH, Lalmohamed A, van Reij EM, Dvorak CC, Savic RM, Zwaveling J, Bredius RG, Egberts AC, Bierings M, Kletzel M, Shaw PJ, Nath CE, Hempel G, Ansari M, Krajinovic M, Theoret Y, Duval M, Keizer RJ, Bittencourt H, Hassan M, Gungor T, Wynn RF, Veys P, Cuvelier GD, Marktel S, Chiesa R, Cowan MJ, Slatter MA, Stricherz MK, Jennissen C, Long-Boyle JR, Boelens JJ. Busulfan Exposure Predicts Event Free Survival and Toxicity after Hematopoietic Cell Transplantation in Children And Young Adults: A Multicenter Retrospective Cohort Analysis. In: 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation. 2016, Valencia, Spain: Nature Publishing Group.
• Boztug H, Sykora K-W, Slatter M, Zecca M, Veys P, Lankester A, Cant A, Skinner R, Wachowiak J, Glogova E, Pötschger U, Peters C. European Society for Blood and Marrow Transplantation Analysis of Treosulfan Conditioning Before Hematopoietic Stem Cell Transplantation in Children and Adolescents With Hematological Malignancies. Pediatric Blood & Cancer 2016, 63(1), 139-148.
• Slatter M, Nademi Z, Leahy TR, Morillo-Gutierrez B, Dunn J, Barge D, Skinner R, Ryan C, Hambleton S, Abinun M, Flood T, Cant A, Gennery A. Haploidentical CD3 TCRαβ and CD19-depleted second stem cell transplant for steroid-resistant acute skin graft versus host disease. Journal of Allergy and Clinical Immunology 2016, 138(2), 603-605.
• Nademi Z, Slatter MA, Dvorak CC, Neven B, Fischer A, Suarez F, Booth C, Rao K, Laberko A, Rodina J, Bertrand Y, Koltan S, Debski R, Flood T, Abinun M, Gennery AR, Hambleton S, Ehl S, Cant AJ. Hematopoietic stem cell transplant in patients with activated PI3K delta syndrome. Journal of Allergy and Clinical Immunology 2016, 139(6), 1046-1049.
• Slatter MA, Engelhardt KR, Burroughs LM, Arkwright PD, Nademi Z, Skoda-Smith S, Hagin D, Kennedy A, Barge D, Flood T, Abinun M, Wynn RF, Gennery AR, Cant AJ, Sansom D, Hambleton S, Torgerson TR. Hematopoietic stem cell transplantation for CTLA4 deficiency. Journal of ALlergy and Clinical Immunology 2016, 138(2), 615-619.
• Abd Hamid IJ, Slatter M, Pearce MS, Gennery A. Long-term immune reconstitution post- hematopoietic stem cell transplantation in IL2RG/JAK3 SCID, Newcastle experience. In: American Society of Pediatric Hematology/Oncology (ASPHO). 2016, Minneapolis, USA: John Wiley & Sons, Inc.
• Abd Hamid IJ, Slatter M, Pearce MS, Gennery A. Long-term immune reconstitution post-hematopoietic stem cell transplantation in IL2RG/JAK3 SCID, Newcastle Experience. In: 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation. 2016, Valencia, Spain: Nature Publishing Group.
• Abd Hamid IJ, Slatter M, Pearce MS, Gennery AR. Long-term immune reconstruction post-hematopoietic stem cell transplantation in IL2RG/JAK3 SCID, Newcastle experience. In: CIS Annual Meeting: Immune Deficiency & Dysregulation North American Conference. 2016, Boston, Massachusetts: Springer.
• Abd Hamid IJ, Slatter M, McKendrick F, Pearce MS, Gennery A. Post-transplant health-related quality of life for different severe combined immunodeficiency genotypes. In: 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation. 2016, Valencia, Spain: Nature Publishing Group.
• Juliana I, Hamid A, Slatter M, McKendrick F, Pearce MS, Gennery A. Post-Transplant Health-Related Quality of Life for Different Severe Combined Immunodeficiency Genotypes. In: American Society of Pediatrics Hematology/Oncology (ASPHO). 2016, Minneapolis, MN, USA: Wiley-Blackwell Publishing Ltd.
• Abd Hamid IJ, Slatter M, McKendrick F, Pearce MS, Gennery AR. Post-Transport health-related quality of life for different severe combined immunodeficiency genotypes. In: CIS Annual Meeting: Immune Deficiency & Dysregulation North American Conference. 2016, Boston, Massachusetts: Springer New York LLC.
• Abd Hamid IJ, Slatter M, Pearce MS, Gennery A. Predictors of survival among individuals with severe combined immunodeficiency disorder undergoing hematopoietic stem cell transplantation. In: 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation. 2016, Valencia, Spain: Nature Publishing Group.
• Morillo-Gutierrez B, Beier R, Rao K, Burroughs L, Schulz A, Ewins AM, Gibson B, Sedlacek P, Krol L, Strahm B, Zaidman I, Kalwak K, Talano JA, Woolfrey A, Fraser C, Meyts I, Muller I, Wachowiak J, Bernardo ME, Veys P, Sykora KW, Gennery AR, Slatter M. Treosulfan-based conditioning for allogeneic HSCT in children with chronic granulomatous disease: a multicenter experience. Blood 2016, 128(3), 440-448.
• Boztug H, Glogova E, Potschger U, Zecca M, Veys P, Lankester A, Cant A, Skinner R, Slatter M, Wachowiak J, Sykora KW, Peters C, EBMT Pediatric Dis Working Party. EBMT metaanalysis of treosulfan conditioning before allogeneic hematopoietic stem cell transplantation in paediatric patients with haematological malignancies. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation. 2015, Istanbul, Turkey: Nature Publishing Group.
• Gambineri E, Mannurita SC, Robertson H, Vignoli M, Haugk B, Lionetti P, Hambleton S, Barge D, Gennery AR, Slatter M, Nademi Z, Flood TJ, Jackson A, Abinun M, Cant AJ. Gut immune reconstitution in immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome after hematopoietic stem cell transplantation. Journal of Allergy and Clinical Immunology 2015, 135(1), 260-262.e8.
• Ferrua F, Courteille V, Janda A, Slatter M, Albert MH, Al-Mousa H, Al-Saud B, Balashov D, Bertrand Y, Booth C, Bordon V, Czogala W, Dogu F, Fasth A, Formankova R, Gozdzik J, Heilmann C, Honig M, Ikinciogullari A, Kalwak K, Keogh SJ, Krivan G, Lange A, Lankester AC, Ljungman P, Meyts I, Neven B, Soncini E, Suarez F, Mahlaoui N, Fischer A, Davies EG, Gennery AR, EBMT IEWP. Haematopoietic stem cell transplantation for CD40 ligand deficiency: results from an EBMT Inborn Errors Working Party (IEWP) study. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation. 2015, Istanbul, Turkey: Nature Publishing Group.
• Morillo-Gutierrez B, Nademi Z, Dunn J, Barge D, Hambleton S, Abinun M, Flood T, Cant AJ, Gennery A, Slatter M. Haploidentical TCRab and CD19 Depleted Stem Cell Transplant for Primary Immunodeficiency-6 cases. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation. 2015, Istanbul, Turkey: Nature Publishing Group.
• Engelhardt KR, Xu YB, Grainger A, Batacchi MGCG, Swan DJ, Willet JDP, Abd Hamid IJ, Agyeman P, Barge D, Bibi S, Jenkins L, Flood T, Abinun M, Slatter M, Gennery AR, Cant AJ, Koref MS, Hambleton S. Identification Of Heterozygous Single- And Multi-exon Deletions In IL7R By Whole Exome Sequencing. In: UKPIN 2015 Meeting. 2015, Belfast, Northern Ireland: Wiley-Blackwell Publishing Ltd.
• Wehr C, Gennery AR, Lindemans C, Schulz A, Hoenig M, Marks R, Recher M, Gruhn B, Holbro A, Heijnen I, Meyer D, Grigoleit G, Einsele H, Baumann U, Witte T, Sykora K-W, Goldacker S, Regairaz L, Aksoylar S, Ardeniz O, Zecca M, Zdziarski P, Meyts I, Matthes-Martin S, Imai K, Kamae C, Fielding A, Seneviratne S, Mahlaoui N, Slatter MA, Gungor T, Arkwright PD, Van Montfrans J, Sullivan KE, Grimbacher B, Cant A, Peter H-H, Finke J, Gaspar HB, Warnatz K, Rizzi M. Multicenter experience in hematopoietic stem cell transplantation for serious complications of common variable immunodeficiency. Journal of Allergy and Clinical Immunology 2015, 135(4), 988-997.e6.
• Strehle EM, Straub V. Recent advances in the management of Duchenne muscular dystrophy. Archives of Disease in Childhood 2015, 100(12), 1173-1177.
• Abinun M, Lilic D, Devlin L, Christie S, Edgar D, Depner M, Fuchs S, Grimbacher B, Cant A, Flood T, Hambleton S, Gennery A, Nademi Z, Slatter M. Successful Allogeneic Haematopoietic Stem Cell Transplantation In A Child With Severe Immunodeficiency 31-C (OMIM # 614162) Due To STAT1-GOF Mutation. In: UKPIN 2015. 2015, Wiley-Blackwell.
• Slatter MA, Boztug H, Potschger U, Sykora KW, Lankester A, Yaniv I, Sedlacek P, Glogova E, Veys P, Gennery AR, Peters C, EBMT Inborn Errors Paediat Dis Wor. Treosulfan-based conditioning regimens for allogeneic haematopoietic stem cell transplantation in children with non-malignant diseases. Bone Marrow Transplantation 2015, 50(12), 1536-1541.
• Ip W, Gaspar HB, Kleta R, Chanudet E, Bacchelli C, Pitts A, Nademi Z, Davies EG, Slatter MA, Amrolia P, Rao K, Veys P, Gennery AR, Qasim W. Variable Phenotype of Severe Immunodeficiencies Associated with RMRP Gene Mutations. Journal of Clinical Immunology 2015, 35(2), 147-157.
• Worth AJJ, Nademi Z, Kammermeier J, Bunn S, Chiesa R, Cant A, Hambleton S, Shah N, Slatter M, Rao K, Gennery A, Elawad M, Amrolia P, Veys P. Allogeneic Stem Cell Transplant Offers Cure for Intractable Childhood Enteropathy. In: 2014 BMT Tandem Meetings. 2014, Dallas, Texas: Elsevier Inc.
• Gennery AR, Slatter MA. Chemotherapy-free conditioning: one step closer. Blood 2014, 124(6), 838-840.
• Ip W, Pitts A, Gaspar HB, Davies EG, Veys P, Slatter MA, Gennery AR, Qasim W. Clinical Presentation and Allogeneic Haematopoietic Stem Cell Transplantation in Cartilage Hair Hypoplasia. In: European Society for Immunodeficiencies. 2014, Prague, Czech Republic: Springer.
• Kharya G, Nademi Z, Leahy T, Brigham K, Barge D, Hambleton S, Abinun M, Flood T, Cant A, Slatter M, Gennery A. Common Gamma chain- and JAK3-deficient SCID, conditioned versus unconditioned transplant: a single centre experience. In: 40th Annual Meeting of the European Group for Blood and Marrow Transplantation. 2014, Milan, Italy: Nature Publishing Group.
• Dvorak CC, Hassan A, Slatter MA, Honig M, Lankester AC, Buckley RH, Pulsipher MA, Davis JH, Gungor T, Gabriel M, Bleesing JH, Bunin N, Sedlacek P, Connell JA, Crawford DF, Notarangelo LD, Pai SY, Hassid J, Veys P, Gennery AR, Cowan MJ. Comparison of outcomes of hematopoietic stem cell transplantation without chemotherapy conditioning by using matched sibling and unrelated donors for treatment of severe combined immunodeficiency. Journal of Allergy and Clinical Immunology 2014, 134(4), 935-943.e15.
• Abinun M, Nademi Z, Flood TJ, Friswell M, Foster HE, Hambleton S, Gennery AR, Cant AJ, Slatter M. Haematopoietic stem cell transplantation (hsct) for severe autoimmune and autoinflammatory syndromes in children. In: 100th J Project Meeting. 2014, Antalya, TURKEY: Springer.
• Ferrua F, Janda A, Courteille V, Slatter M, Albert MH, Al-Mousa H, Al-Saud B, Balashov D, Bertrand Y, Bordon V, Czogala W, Dogu F, Fasth A, Formankova R, Gozdzik J, Heilmann C, Honig M, Ikinciogullari A, Kalwak K, Keogh SJ, Krivan G, Lankester AC, Meyts I, Neven B, Suarez F, Mahlaoui N, Fischer A, Gennery AR. Haematopoietic Stem Cell Transplantation for CD40 Ligand Deficiency: Results from an EBMT/ESID Inborn Error Working Party Study. In: European Society for Immunodeficiencies. 2014, Prague, Czech Republic: Springer.
• Elfeky R, Nademi Z, Brigham K, Barge D, Hambleton S, Abinun M, Flood T, Cant A, Slatter M, Gennery A. Haematopoietic stem cell transplantation for RAG1/2 severe combined immunodeficiency or Omenn syndrome: a single centre experience. In: 40th Annual Meeting of the European Group for Blood and Marrow Transplantation. 2014, Milan, Italy: Nature Publishing Group.
• Kharya G, Nademi Z, Leahy TR, Dunn J, Barge D, Schulz A, Cant A, Gennery A, Slatter M. Haploidentical T-cell alpha beta receptor and CD19-depleted stem cell transplant for Wiskott-Aldrich syndrome. Journal of Allergy and Clinical Immunology 2014, 134(5), 1199-1201.
• Morillo-Gutierrez B, Nademi Z, Dunn J, Barge D, Hambleton S, Abinum M, Flood T, Cant AJ, Gennery AR, Slatter M. Haploidentical TCR Alfa/Beta and CD19 Depleted Stem Cell Transplant for Primary Immunodeficiency-4 Cases. In: European Society for Immunodeficiencies. 2014, Prague, Czech Republic: Springer.
• Slack J, Slatter MA, Gaspar B, Albert M, Ghosh S, Meisel R, Guengoer T, Karasu G, Drabko K, Lange A, Kalwak K, Pasic S, Heilmann C, Imai K, Shaw P, Schultz K, Eapen M, Horwitz E, Gennery AR, IEWP EBMT, CIBMTR. International study on outcomes of Haematopoietic Stem Cell transplant for DNA-DSB repair defects. In: 40th Annual Meeting of the European Group for Blood and Marrow Transplantation. 2014, Milan, Italy: Nature Publishing Group.
• Lane JR, Evans PTG, Nademi Z, Barge D, Jackson A, Hambleton S, Flood TJ, Cant AJ, Abinun M, Slatter MA, Gennery AR. Low-Dose Serotherapy Improves Early Immune Reconstitution after Cord Blood Transplantation for Primary Immunodeficiencies. Biology of Blood and Marrow Transplantation 2014, 20(2), 243-249.
• Dhir S, Slatter M, Skinner R. Recent advances in the management of graft-versus-host disease. Archives of Disease in Childhood 2014, 99(12), 1150-1157.
• Gungor T, Teira P, Slatter M, Stussi G, Stepensky P, Moshous D, Vermont C, Ahmad I, Shaw PJ, da Cunha JMT, Schlegel PG, Hough R, Fasth A, Kentouche K, Gruhn B, Fernandes JF, Lachance S, Bredius R, Resnick IB, Belohradsky BH, Gennery A, Fischer A, Gaspar HB, Schanz U, Seger R, Rentsch K, Veys P, Haddad E, Albert MH, Hassan M, Inborn Errors Working Party Europe. Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study. Lancet 2014, 383(9915), 436-448.
• Morillo-Gutierrez B, Worth A, Slatter M, Nademi Z, Flood T, Valappil M, Waugh S, Breuer J, Gaspar B, Gennery A. Rotavirus Vaccine Serotype Infection in SCID Patients Following Introduction of Universal Rotavirus Vaccination in UK-4 Cases. In: 16th Biennial Meeting of the European Society for Immunodeficiences (ESID 2014). 2014, Prague, Czech Republic: Springer.
• Nademi Z, Slatter M, Gambineri E, Mannurita SC, Barge D, Hodges S, Bunn S, Thomas J, Haugk B, Hambleton S, Flood T, Cant A, Abinun M, Gennery A. Single centre experience of haematopoietic SCT for patients with immunodysregulation, polyendocrinopathy, enteropathy, X-linked syndrome. Bone Marrow Transplantation 2014, 49(2), 310-312.
• Slatter MA, Gennery AR. Advances in hematopoietic stem cell transplantation for primary immunodeficiency. Expert Review of Clinical Immunology 2013, 9(10), 991-999.
• Sinha A, Abinun M, Gennery AR, Barge D, Slatter M, Cheetham T. Graves' Immune Reconstitution Inflammatory Syndrome in Childhood. Thyroid 2013, 23(8), 1010-1014.
• Slatter M, Nademi Z, Patel S, Barge D, Valappil M, Brigham K, Hambleton S, Clark J, Flood T, Cant A, Abinun M, Gennery A. Haploidentical hematopoietic stem cell transplantation can lead to viral clearance in severe combined immunodeficiency. Journal of Allergy and Clinical Immunology 2013, 131(6), 1705-1708.e1.
• Lown R, Veys P, Slatter M, Wynn R, Bloor A, Perry J, Pearce R, Kirkland K, Shaw B. High Engraftment Rates Following Second Allogeneic Transplants for Graft Failure Result in Good Outcomes, on Behalf of the BSBMT. In: BMT Tandem Meetings. 2013, Salt Lake City, Utah, USA: Elsevier Inc.
• Peters C, Sykora KW, Veys P, Lankester A, Slatter M, Skinner R, Wachowiak J, Poetschger U. Treosulfan for Conditioning in Children and Adolescents Before Hematopoietic Stem Cell Transplantation (HSCT). In: BMT Tandem Meetings. 2013, Salt Lake City, Utah, USA: Elsevier Inc.
• Hambleton S, McDonald DO, Morgan NV, Griffin H, Singh-Dang T, Grainger A, Reynard L, Gennery AR, Slatter M, Flood TJ, McKiernan P, Barge D, Abinun M, Hackett S, Loughlin J, Lakey J, Cant AJ, Santibanez-Koref M. Autosomal recessive combines immunodeficiency due to loss of function mutation in Tripeptidyl Peptidase II. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
• Barge D, Bainbridge M, Slatter M, Gennery A, Hambleton S, Abinun M, Flood T, Cant A, Spickett G. Class switch memory B cells in assessing humoral immunity post HSCT for primary immune deficiency. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
• Mannurita SC, Robertson H, Vignoli M, Hambleton S, Gennery AR, Slatter M, Nademi Z, Barge D, Abinun M, Cant AW, Gambineri E. Gut immune reconstitution in Ipex Syndrome after HSCT. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer New York LLC.
• Gambineri E, Mannurita SC, Robertson H, Vignoli M, Hambleton S, Gennery A, Slatter M, Nademi Z, Barge D, Abinun M, Cant AJ. Gut Immune Reconstitution in IPEX Syndrome After HSCT. In: Annual Meeting of the Clinical Immunology Society (CIS). 2012, Chicago, Illinois, USA: Springer.
• Matthews CJ, Abinun M, Dunn AN, Green MA, Morris J, Slatter MA, Hambleton S, Carter V, Howell WM. Hematopoietic stem cell transplantation for primary immunodeficiency: A sibling donor mismatched at HLA-A due to recombination. In: 16th International HLA and Immunogenetics Workshop. 2012, Liverpool, UK: Wiley-Blackwell Publishing, Inc.
• Moreira D, Slatter M, Nademi Z, Brigham K, Barge D, Jackson A, Flood T, Cant A, Abinun M, Hambleton S, Gennery A. Immune reconstitution and clinical outcome after HSCT infusion for severe combined immunodeficiency in Newcastle. In: Biology of Blood and Marrow Transplantation: BMT Tandem Meeting. 2012, San Diego, California, USA: Elsevier Inc.
• Esteves I, Badawy S, Nademi Z, Barge D, Hambleton S, Flood T, Cant AJ, Abinun M, Slatter M, Gennery AR. Immunological reconstitution after haematopoietic stem cell transplantation for CD40L deficiency. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
• Cole TS, Johnstone IC, Pearce MS, Fulton B, Cant AJ, Gennery AR, Slatter MA. Outcome of children requiring intensive care following haematopoietic SCT for primary immunodeficiency and other non-malignant disorders. Bone Marrow Transplantation 2012, 47(1), 40-45.
• Lane J, Slatter M, Nademi Z, Tierney P, Barge D, Hambleton S, Flood T, Cant A, Abinun M, Jackson G, Collin M, Gennery A. Outcome of haematopoietic stem cell transplantation in patients with chronic granulomatous disease at a national centre. In: 38th Annual Meeting of the European Group for Blood and Marrow Transplantation (EBMT). 2012, Geneva, Switzerland: Nature Publishing Group.
• Maggina P, Nademi Z, Barge D, Hambleton S, Flood T, Cant AJ, Abinun M, Slatter M, Gennery A. Outcome of haematopoietic stem cell transplantation in patients with major histocompatibility class II deficiency at a national centre. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
• Sturgess K, Slatter M, Bigley V, Dickinson R, Haniffa M, McGovern N, Jardine L, Jackson G, Cant A, Gennery A, Hambleton S, Collin M. Reduced-intensity haematopoietic stem cell transplant rescues immune function and corrects pulmonary alveolar proteinosis in DCML deficiency/GATA 2 mutation. In: 38th Annual Meeting of the European Group for Blood and Marrow Transplantation (EBMT). 2012, Geneva, Switzerland: Nature Publishing Group.
• Slatter M, Rao K, Krol L, Sedlacek P, Nademi Z, Chiesa R, Amrolia P, Flood T, Abinun M, Cant A, Hambleton S, Gaspar H, Veys P, Gennery A. Treosulfan, fludarabine and alemtuzumab conditioning for haematopoietic stem cell transplantation in children with chronic granulomatous disease: experience in three centres. In: 38th Annual Meeting of the European Group for Blood and Marrow Transplantation (EBMT). 2012, Geneva, Switzerland: Nature Publishing Group.
• Booth C, Gilmour KC, Veys P, Gennery AR, Slatter MA, Chapel H, Heath PT, Steward CG, Smith O, O'Meara A, Kerrigan H, Mahlaoui N, Cavazzana-Calvo M, Fischer A, Moshous D, Blanche S, Pachlopnick-Schmid J, Latour S, de Saint-Basile G, Albert M, Notheis G, Rieber N, Strahm B, Ritterbusch H, Lankester A, Hartwig NG, Meyts I, Plebani A, Soresina A, Finocchi A, Pignata C, Cirillo E, Bonanomi S, Peters C, Kalwak K, Pasic S, Sedlacek P, Jazbec J, Kanegane H, Nichols KE, Hanson IC, Kapoor N, Haddad E, Cowan M, Choo S, Smart J, Arkwright PD, Gaspar HB. X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management and outcome of the disease. Blood 2012, 117(1), 53-62.
• Subbarayan A, Colarusso G, Hughes SM, Gennery AR, Slatter M, Cant AJ, Arkwright PD. Clinical Features That Identify Children With Primary Immunodeficiency Diseases. Pediatrics 2011, 127(5), 810-816.
• Slatter MA, Cant AJ. Hematopoietic stem cell transplantation for primary immunodeficiency diseases. In: Casanova, J.L., Conley, M.E., Notarengelo, L, ed. The Year in Human and Medical Genetics: Inborn Errors of Immunity I. Oxford, UK: Wiley-Blackwell, 2011, pp.122-131.
• Lane JP, Evans PTG, Slatter MA, Barge D, Jackson A, Hambleton S, Flood T, Abinun M, Cant J, Gennery A. Immune reconstitution post umbilical cord blood stem cell transplantation for primary immunodeficiency in a national centre. In: Bone Marrow Transplantation: 37th European Group for Bone and Marrow Transplantation. 2011, Paris, France: Nature Publishing Group.
• Moratto D, Giliani S, Bonfim C, Mazzolari E, Fischer A, Ochs HD, Cant AJ, Thrasher AJ, Cowan MJ, Albert MH, Small T, Pai SY, Haddad E, Lisa A, Hambleton S, Slatter M, Cavazzana-Calvo M, Mahlaoui N, Picard C, Torgerson TR, Burroughs L, Koliski A, Zanis-Neto J, Porta F, Qasim W, Veys P, Kavanau K, Hönig M, Schulz A, Friedrich W, Notarangelo LD. Long-term outcome and lineage-specific chimerism in 194 Wiskott-Aldrich Syndrome patients treated by hematopoietic cell transplantation between 1980-2009: an international collaborative study. Blood 2011, 118(6), 1675-1684.
• Brown L, Xu-Bayford J, Allwood Z, Slatter M, Cant A, Davies EG, Veys P, Gennery AR, Gaspar HB. Neonatal diagnosis of severe combined immunodeficiency leads to significantly improved survival outcome: the case for newborn screening. Blood 2011, 117(11), 3243-3246.
• Brown L, Xu-Bayford J, Allwood Z, Slatter M, Cant A, Davies EG, Veys P, Gennery AR, Gaspar HB. Neonatal Diagnosis of Severe Combined Immunodeficiency Leads to Significantly Improved Survival Outcome: The Case for Newborn Screening [editorial comment]. Obstetrical & Gynecological Survey 2011, 66(7), 398-399.
• Slatter MA, Angus B, Windebank K, Taylor A, Meaney C, Lester T, Norbury G, Hambleton S, Abinun M, Flood TJ, Cant AJ, Gennery AR. Polymorphous lymphoproliferative disorder with Hodgkin-like features in common gamma-chain-deficient severe combined immunodeficiency. Journal of Allergy and Clinical Immunology 2011, 127(2), 533-535.
• Sturgess K, Slatter M, Bigley V, Haniffa M, Wang XN, Dickinson R, McGovern N, Jardine L, Pagan S, Chua I, Wallis J, Lordan J, Morgan C, Cant A, Gennery A, Edmondson R, Bacon C, Black F, Kirkham N, Jackson GH, Hambleton S, Collin MP. Reduced Intensity Hematopoietic Stem Cell Transplant Rescues Immune Function and Corrects Pulmonary Alveolar Proteinosis in DCML Deficiency/GATA 2 Mutation. In: Blood: 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH). 2011, San Diego, California, USA: American Society of Hematology.
• Slatter MA, Rao K, Amrolia P, Flood T, Abinun M, Hambleton S, Nademi Z, Goulden N, Davies G, Qasim W, Gaspar HB, Cant A, Gennery AR, Veys P. Treosulfan-based conditioning regimens for hematopoietic stem cell transplantation in children with primary immunodeficiency: United Kingdom experience. Blood 2011, 117(16), 4367-4375.
• Nademi Z, Slatter M, Gennety A, Flood T, Hambleton S, Clark J, Friswell M, Foster H, Cant A, Abinun M. Autologous (T-cell depleted) or allogeneic haematopoietic stem cell transplantation for treatment of recalcitrant, severe autoimmune/rheumatic disorders in children?. In: 36th Annual Meeting of the European Group for Blood and Marrow Transplantat/9th Meeting of the EBMT Data Management Group/26th Meeting of the EBMT Nurses Group/2nd EBMT Quality Management Meeting. 2010, Vienna, Austria: Bone Marrow Transplantation, Nature Publishing Group.
• Bordon V, Gennery AR, Slatter MA, Vandecruys E, Laureys G, Veys P, Waseem Q, Friedrich W, Wulfraat NM, Scherer F, Cant AJ, Fischer A, Cavazanna-Calvo M, Bredius RGM, Notarangelo LD, Mazzolari E, Neven B, Tayfun G. Clinical and immunologic outcome of patients with cartilage hair hypoplasia after hematopoietic stem cell transplantation. Blood 2010, 116(1), 27-35.
• Vignoli M, Mannurita SC, Bianchi L, Bacchetta R, Cecconi M, Tommasini A, Abinun M, Gennery A, Hambleton S, Slatter M, Cant A, de Martino M, Gambineri E. Exploring 'IPEX-like Syndrome': What is Beyond FOXP3 Gene?. In: 10th Annual Meeting of the Federation of Clinical Immunology Societies. 2010, Boston, MA: Clinical Immunology, Academic Press.
• Janda A, Sedlacek P, Honig M, Friedrich W, Champagne M, Matsumoto T, Fischer A, Neven B, Contet A, Bensoussan D, Bordigoni P, Loeb D, Savage W, Jabado N, Bonilla FA, Slatter MA, Davies EG, Gennery AR. Multicenter survey on the outcome of transplantation of hematopoietic cells in patients with the complete form of DiGeorge anomaly. Blood 2010, 116(13), 2229-2236.
• Patel S, Slatter M, Valappil M, Waugh S. Persistent adenoviraemia in an infant following haematopoietic stem cell transplantation. Journal of Clinical Virology 2010, 47(1), 1-3.
• Slatter MA, Gennery AR. Primary immunodeficiencies associated with DNA-repair disorders. Expert Reviews in Molecular Medicine 2010, 12, e9.
• Slatter MA, Gennery AR. Primary Immunodeficiency Syndromes. In: Diseases of DNA repair. Berlin, Germany: Springer, 2010, pp.146-165.
• Gennery AR, Slatter MA, Grandin L, Taupin P, Cant AJ, Veys P, Amrolia PJ, Gaspar HB, Davies EG, Friedrich W, Hoenig M, Notarangelo LD, Mazzolari E, Porta F, Bredius RGM, Lankester AC, Wulffraat NM, Seger R, Gungor T, Fasth A, Sedlacek P, Neven B, Blanche S, Fischer A, Cavazzana-Calvo M, Landais P, and Members of the Inborn Errors Working Party. Transplantation of hematopoietic stem cells and long-term survival for primary immunodeficiencies in Europe: Entering a new century, do we do better?. Journal of Allergy and Clinical Immunology 2010, 126(3), 602-610.
• Slatter M, Rao K, Amrolia P, Flood T, Abinun M, Cant A, Hambleton S, Goulden N, Davies G, Qasim W, Gasper HB, Gennery A, Veys P. UK experience of treosulfan-based conditioning regimens in children with primary immunodeficiency. In: 36th Annual Meeting of the European Group for Blood and Marrow Transplantat/9th Meeting of the EBMT Data Management Group/26th Meeting of the EBMT Nurses Group/2nd EBMT Quality Management Meeting. 2010, Vienna, Austria: Bone Marrow Transplantation, Nature Publishing Group.
• Slatter MA, Bhattacharya A, Flood TJ, Spickett GP, Cant AJ, Abinum M, Gennery AR. Polysaccharide antibody responses are impaired post bone marrow transplantation for severe combined immunodefiency, but not other primary immunodefeciencies. Bone Marrow Transplantation 2003, 32(2), 225-229.
• Bhattacharya A, Slatter M, Curtis A, Chapman CE, Barge D, Jackson A, Flood TJ, Abinun M, Cant AJ, Gennery AR. Successful umbilical cord blood stem cell transplantation for chronic granulomatous disease. Bone Marrow Transplantation 2003, 31(5), 403-405.