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Staff Profile

Professor Jelena Mann

Professor of Epigenetics

  • Email: [email protected]
  • Telephone: +44 (0) 191 208 5902
  • Fax: +44 (0) 191 208 0723
  • Personal Website: http://research.ncl.ac.uk/fibrosislab
  • Address: Liver Research Group
    Institute of Cellular Medicine
    4th Floor, William Leech Building
    Medical School
    Newcastle University
    Newcastle-upon-Tyne
    NE2 4HH
Background

Area of expertise

I am interested in delineating epigenetic signalling pathways that trigger fibrogenesis and in doing so, discovering molecular control of fibrogenesis and associated signalling pathways that can be targeted with new as well as existing drugs. More recently we have also embarked on studies that test the ability of environmental factors to affect transgenerational inheritance of predisposition to liver fibrosis. Adaptation to environmental insults is critical for ensuring fitness and survival of the species, however it is currently not clear if predisposition to development of fibrosis exists or indeed if existence of disease in previous generations alters such predisposition.

 

Education

  • 1994-1997 - BSc Biochemistry, 1st class
  • 1997-2001 - PhD in Medicine, University of Southampton

Previous appointments

  • University of Leeds, Postdoctoral Research Assistant (31/01/2001 to 31/12/2002)
  • Wellcome Trust Postdoctoral Research Assistant, University of Southampton (01/01/2003 to 31/08/2004)
  • University of Southampton Personal Fellowship 01/09/2004 to 01/10/2006

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Publications