Staff Profile

Dr Djordje Jakovljevic is a Professor and Research Theme Lead in Cardiovascular and Lifestyle Medicine at the Institute for Health and Wellbeing, Faculty of Health and Life Sciences of Coventry University. We endeavour multidisciplinary cardiovascular research to reduce the burden of cardiovascular disease and heart failure, leading to improved length and quality of life of people across the world.

Research Interests

Development, evaluation and implementation of novel interventions and technologies to improve prevention, diagnosis and management of cardiovascular diseases. Our research has particularly focused on heart failure, from improving diagnosis and rehabilitation, to treatment and recovery of advanced heart failure using mechanical circulatory support. The research has further improved understanding of cardiovascular physiological and molecular changes with ageing and their malleability with lifestyle and pharmacological interventions to prevent onset of cardiovascular and metabolic diseases. 

Our Vision

Develop and deliver opportunities through globally significant interdisciplinary research and innovation in cardiovascular and lifestyle medicine in order to improve health across the life course.

Our mission

Translate research findings and innovation excellence into clinical practice to improve length and quality of life of people across the world.

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• Charman S, Okwose N, Maniatopoulos G, Graziadio S, Metzler T, Banks H, Vale L, MacGowan GA, Seferovic PM, Fuat A, Deaton C, Mant J, Hobbs RFD, Jakovljevic DG. Opportunities and challenges of a novel cardiac output response to stress (CORS) test to enhance diagnosis of heart failure in primary care: Qualitative study. BMJ Open 2019, 9(4), e028122.
• Koshy A, Cruz NB, Okwose NC, Fernandez OG, Green T, Woods A, Robinson-Smith N, Tovey S, McDiarmid A, Parry G, Schueler S, Jakovljevic DG, MacGowan GA. Left Ventricular Filling Pressures Contribute to Exercise Limitation in Patients with Continuous Flow Left Ventricular Assist Devices. ASAIO Journal 2019, 66(3), 247-252.
• Koshy A, Green T, Toms A, Cassidy S, Schueler S, Jakovljevic D, MacGowan GA. The role of exercise hemodynamics in assessing patients with chronic heart failure and left ventricular assist devices. Expert Review of Medical Devices 2019, 16(10), 891-898.
• Okwose NC, Avery L, O'Brien N, Cassidy S, Charman SJ, Bailey K, Velicki L, Olivotto I, Brennan P, MacGowan GA, Jakovljevic DG. Acceptability, Feasibility and Preliminary Evaluation of a Novel, Personalised, Home-Based Physical Activity Intervention for Chronic Heart Failure (Active-at-Home-HF): a Pilot Study. Sports Medicine Open 2019, 5, 45.
• Koshy A, Okwose NC, Nunan D, Toms A, Brodie DA, Doherty P, Seferovic P, Ristic A, Velicki L, Filipovic N, Popovic D, Skinner J, Bailey K, MacGowan GA, Jakovljevic DG. Association between heart rate variability and haemodynamic response to exercise in chronic heart failure. Scandinavian Cardiovascular Journal 2019, 53(2), 77-82.
• Ferrera C, Gonzalez Fernandez O, Bouzas N, Castrodeza J, Green T, Woods A, Robinson-Smith N, Tovey S, Jakovljevic DG, Shah A, Booth K, Parry G, Schueler S, MacGowan GA. Neutrophil to Lymphocyte Ratio Is Related to Thrombotic Complications and Survival in Continuous Flow Left Ventricular Assist Devices. ASAIO Journal 2019, 66(2), 199-204.
• Parovic M, Okwose NC, Bailey K, Velicki L, Seferovic PM, MacGowan GA, Jakovljevic DG. NT-proBNP is a weak indicator of cardiac function and haemodynamic response to exercise in chronic heart failure. ESC Heart Failure 2019, 6(2), 449-454.
• Gao X, Jakovljevic DG, Beard DA. Cardiac Metabolic Limitations Contribute to Diminished Performance of the Heart in Aging. Biophysical Journal 2019, 117(12), 2295-2302.
• Cassidy S, Okwose N, Scragg J, Houghton D, Ashley K, Trenell MI, Jakovljevic DG, Hallsworth K, Avery L. Assessing the feasibility and acceptability of Changing Health for the management of prediabetes: protocol for a pilot study of a digital behavioural intervention. Pilot and Feasibility Studies 2019, 5, 139.
• Greenwald R, Hayat MJ, Dons E, Giles L, Villar R, Jakovljevic DG, Good N. Estimating minute ventilation and air pollution inhaled dose using heart rate, breath frequency, age, sex and forced vital capacity: A pooled-data analysis. PLoS ONE 2019, 14(7), e0218673.
• MacGowan GA, Jakovljevic DG. Exercise Hemodynamics to Evaluate the Breathless Patient: Defining the Normal Pulmonary Arterial Wedge Pressure. Journal of Cardiac Failure 2019, 25(2), 123-124.
• Charman SJ, Okwose NC, Stefanetti RJ, Bailey K, Skinner J, Ristic A, Seferovic PM, Scott M, Turley S, Fuat A, Mant J, Hobbs FDR, MacGowan GA, Jakovljevic DG. A novel cardiac output response to stress test developed to improve diagnosis and monitoring of heart failure in primary care. ESC Heart Failure 2018, 5(4), 703-712.
• Jones C, Markovic M, Charman S, Okwose N, Ivkovic S, Ropret R, Markovic B, Mandaric S, Grbovic M, MacGowan GA, Jakovljevic DG. Cardiac function is not associated with glucose control in older women. Experimental Gerontology 2019, 116, 31-36.
• Okwose NC, Zhang J, Chowdhury S, Houghton D, Ninkovic S, Jakovljevic S, Jevtic B, Ropret R, Eggett C, Bates M, MacGowan G, Jakovljevic D. Reproducibility of Inert Gas Rebreathing Method to Estimate Cardiac Output at Rest and During Cardiopulmonary Exercise Stress Testing. International Journal of Sports Medicine 2019, 40(2), 125-132.
• Shaw A, Houghton D, Hallsworth K, Jakovljevic DG, Trenell MI, Cassidy S. Adiposity predicts low cardiorespiratory fitness in individuals with metabolic diseases. Diabetes Research and Clinical Practice 2018, 146, 300-304.
• Velicki L, Jakovljevic DG, Milosavljevic AM, Todic M, Rajic J, Fabri M. Dynamic right ventricular outflow tract obstruction caused by a large interventricular membranous septal aneurysm. Netherlands Heart Journal 2018, 26(11), 575-576.
• Cassidy S, Vaidya V, Houghton D, Zalewski P, Seferovic JP, Hallsworth K, MacGowan GA, Trenell MI, Jakovljevic DG. Unsupervised high-intensity interval training improves glycaemic control but not cardiovascular autonomic function in type 2 diabetes patients: A randomised controlled trial. Diabetes and Vascular Disease Research 2018, 16(1), 69-76.
• Suryanegara J, Cassidy S, Ninkovic V, Popovic D, Grbovic M, Okwose N, Trenell MI, MacGowan GG, Jakovljevic DG. High intensity interval training protects the heart during increased metabolic demand in patients with type 2 diabetes: a randomised controlled trial. Acta Diabetologica 2019, 56(3), 321-329.
• Andric S, Tesic D, Somer D, Srdanovic I, Miljkovic T, Jakovljevic DG, Velicki L. Ventriculoatrial synchrony induced heart failure. Acta Clinica Belgica: International Journal of Clinical and Laboratory Medicine 2018, 73(6), 439-443.
• Jakovljevic DG, Yacoub MH, Schueler S, MacGowan AG, Velicki L, Seferovic PM, Hothi S, Tzeng BT, Brodie DA, Birks EJ, Tan LB. Left Ventricular Assist Device as a Bridge to Recovery for Patients With Advanced Heart Failure. Journal of the American College of Cardiology 2017, 69(15), 1924-1933.
• Nathania M, Hollingsworth KG, Bates M, Eggett C, Trenell MI, Velicki L, Seferovic PM, MacGowan GA, Turnbull DM, Jakovljevic DG. Impact of age on the association between cardiac high-energy phosphate metabolism and cardiac power in women. Heart 2018, 104(2), 111-118.
• McCoy J, Bates M, Eggett C, Siervo M, Cassidy S, Newman J, Moore SA, Gorman G, Trenell MI, Velicki L, Seferovic PM, Cleland JGF, MacGowan GA, Turnbull DM, Jakovljevic DG. Pathophysiology of exercise intolerance in chronic diseases: the role of diminished cardiac performance in mitochondrial and heart failure patients. Open Heart 2017, 4, e000632.
• Jakovljevic DG. Physical activity and cardiovascular aging: Physiological and molecular insights. Experimental Gerontology 2018, 109, 67-74.
• Okwose NC, Chowdhury S, Houghton D, Trenell MI, Eggett C, Bates M, Macgowan GA, Jakovljevic DG. Comparison of cardiac output estimates by bioreactance and inert gas rebreathing methods during cardiopulmonary exercise testing. Clinical Physiology and Functional Imaging 2018, 38(3), 483-490.
• Oggioni C, Jakovljevic DG, Klonizakis M, Ashor AW, Ruddock A, Ranchordas M, Williams E, Siervo M. Dietary nitrate does not modify blood pressure and cardiac output at rest and during exercise in older adults: a randomised cross-over study. International Journal of Food Sciences and Nutrition 2018, 69(1), 74-83.
• Njemanze H, Warren C, Eggett C, MacGowan GA, Bates MGD, Siervo M, Ivkovic S, Trenell MI, Jakovljevic DG. Age-related decline in cardiac autonomic function is not attenuated with increased physical activity. Oncotarget 2016, 7(47), 76390-76397.
• Perkins RE, Hollingsworth KG, Eggett C, MacGowan GA, Bates MG, Trenell MI, Jakovljevic DG. Relationship between bioreactance and magnetic resonance imaging stroke volumes. British Journal of Anaesthesia 2016, 117(1), 134-136.
• Houghton D, Jones TW, Cassidy S, Siervo M, MacGowan GA, Trenell MI, Jakovljevic DG. The effect of age on the relationship between cardiac and vascular function. Mechanisms of Ageing and Development 2016, 153, 1-6.
• Ninkovic VM, Ninkovic SM, Miloradovic V, Stanojevic D, Babic M, Giga V, Dobric M, Trenell MI, Lalic N, Seferovic PM, Jakovljevic DG. Prevalence and risk factors for prolonged QT interval and QT dispersion in patients with type 2 diabetes. Acta Diabetologica 2016, 53(5), 737-744.
• Charman SJ, van Hees VT, Quinn L, Dunford JR, Bawamia B, Veerasamy M, Trenell MI, Jakovljevic DG, Kunadian V. The effect of percutaneous coronary intervention on habitual physical activity in older patients. BMC Cardiovascular Disorders 2016, 16(1), 248.
• Siervo M, Oggioni C, Jakovljevic DG, Trenell M, Mathers JC, Houghton D, Celis-Morales C, Ashor AW, Ruddock A, Ranchordas M, Klonizakis M, Williams EA. Dietary nitrate does not affect physical activity or outcomes in healthy older adults in a randomized, cross-over trial. Nutrition Research 2016, 36(12), 1361-1369.
• Moore SA, Jakovljevic DG, Ford GA, Rochester L, Trenell MI. Exercise induces peripheral muscle but not cardiac output adaptations after stroke. A randomised controlled pilot trial. Archives of Physical Medicine and Rehabilitation 2016, 97(4), 596-603.
• Jones T, Houghton D, Cassidy S, MacGowan GA, Trenell MI, Jakovljevic DG. Bioreactance is a reliable method for estimating cardiac output at rest and during exercise. British Journal of Anaesthesia 2015, 115(3), 386-391.
• Jakovljevic DG, Papakonstantinou L, Blamire AM, MacGowan GA, Taylor R, Hollingsworth KG, Trenell MI. Effect of Physical Activity on Age-Related Changes in Cardiac Function and Performance in Women. Circulation: Cardiovascular Imaging 2015, 8, e002086.
• Newman J, Galna B, Jakovljevic D, Bates M, Schaefer A, McFarland R, Turnbull D, Trenell M, Taylor R, Rochester L, Gorman G. Preliminary Evaluation of Clinician Rated Outcome Measures in Mitochondrial Disease. Journal Of Neuromuscular Diseases 2015, 2(2), 151-155.
• Jakovljevic DG, Trenell MI, MacGowan GA. Bioimpedance and bioreactance methods for monitoring cardiac output. Best Practice & Research: Clinical Anaesthesiology 2014, 28(4), 381-394.
• Cassidy S, Thoma C, Hallsworth K, Parikh J, Hollingsworth KG, Taylor R, Jakovljevic DG, Trenell MI. High intensity intermittent exercise improves cardiac structure and function and reduces liver fat in patients with type 2 diabetes: a randomised controlled trial. Diabetologia 2016, 59(1), 56-66.
• Cassidy S, Hallsworth K, Thoma C, MacGowan GA, Hollingsworth KG, Day CP, Taylor R, Jakovljevic DG, Trenell MI. Cardiac structure and function are altered in type 2 diabetes and Non-alcoholic fatty liver disease and associate with glycemic control. Cardiovascular Diabetology 2015, 14, 23.
• Moore SA, Hallsworth K, Jakovljevic DG, Blamire AM, He JB, Ford GA, Rochester L, Trenell MI. Effects of Community Exercise Therapy on Metabolic, Brain, Physical, and Cognitive Function Following Stroke: A Randomized Controlled Pilot Trial. Neurorehabilitation & Neural Repair 2015, 29(7), 623-635.
• Jakovljevic DG, McDiarmid A, Hallsworth K, Seferovic PM, Ninkovic VM, Parry G, Schueler S, Trenell MI, MacGowan GA. Effect of Left Ventricular Assist Device Implantation and Heart Transplantation on Habitual Physical Activity and Quality of Life. American Journal of Cardiology 2014, 114(1), 88-93.
• Ashor AW, Lara J, Siervo M, Celis-Morales C, Oggioni C, Jakovljevic DG, Mathers JC. Exercise Modalities and Endothelial Function: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials. Sports Medicine 2015, 45(2), 279-296.
• Galna B, Newman J, Jakovljevic DG, Bates MG, Schaefer AM, McFarland R, Turnbull DM, Trenell MI, Gorman GS, Rochester L. Discrete gait characteristics are associated with m.3243A > G and m.8344A > G variants of mitochondrial disease and its pathological consequences. Journal of Neurology 2014, 261(1), 73-82.
• Nunan D, Sandercock GR, George RS, Jakovljevic DG, Donovan G, Bougard R, Yacoub MH, Brodie DA, Birks EJ. Cardiovascular autonomic control in patients undergoing left ventricular assist device (LVAD) support and pharmacologic therapy. International Journal of Cardiology 2013, 168(4), 4145-4149.
• Bates MG, Newman JH, Jakovljevic DG, Hollingsworth KG, Alston CL, Zalewski P, Klawe JJ, Blamire AM, Macgowan GA, Keavney BD, Bourke JP, Schaefer A, McFarland R, Newton JL, Turnbull DM, Taylor RW, Trenell MI, Gorman GS. Defining cardiac adaptations and safety of endurance training in patients with m.3243A>g-related mitochondrial disease. International Journal of Cardiology 2013, 168(4), 3599-3608.
• Jakovljevic DG, Hallsworth K, Zalewski P, Thoma C, Klawe J, Day CP, Newton J, Trenell MI. Resistance exercise improves autonomic regulation at rest and haemodynamic response to exercise in non-alcoholic fatty liver disease. Clinical Science 2013, 125(3), 143-149.
• Campbell MD, Walker M, Trenell MI, Jakovljevic DG, Stevenson EJ, Bracken RM, Bain SC, West DJ. Large pre- and postexercise rapid-acting insulin reductions preserves glycemia and prevents early- but not late-onset hypoglycemia in patients with type 1 diabetes. Diabetes Care 2013, 36(8), 2217-2224.
• Bates MG, Hollingsworth KG, Newman J, Jakovljevic DG, Blamire AM, MacGowan GA, Keavney BD, Chinnery PF, Turnbull DM, Taylor RW, Trenell MI, Gorman GS. Concentric hypertrophic remodeling and subendocardial dysfunction in mitochondrial DNA point mutation carriers. European Heart Journal - Cardiovascular Imaging 2013, 14(7), 650-658.
• Detko E, OHara JP, Thelwall PE, Smith FE, Jakovljevic DG, King RF, Trenell MI. Liver and muscle glycogen repletion using ¹³C magnetic resonance spectroscopy following ingestion of maltodextrin, galactose, protein and amino acids. British Journal of Nutrition 2013, 110(5), 848-855.
• Klasnja AV, Jakovljevic DG, Barak OF, Popadic-Gacesa JZ, Lukac DD, Grujic NG. Cardiac power output and its response to exercise in athletes and non-athletes. Clinical Physiology and Functional Imaging 2013, 33(3), 201-205.
• Hallsworth K, Hollingsworth KG, Thoma C, Jakovljevic DG, MacGowan GA, Anstee QM, Taylor R, Day CP, Trenell MI. Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease. Journal of Hepatology 2013, 58(4), 757-762.
• Jakovljevic DG, Moore SA, Tan LB, Rochester L, Ford GA, Trenell MI. Discrepancy between cardiac and physical functional reserves in stroke. Stroke 2012, 43, 1422-1425.
• Jakovljevic DG, Moore SA, Trenell MI. Response to Letter Regarding Article, "Discrepancy Between Cardiac and Physical Functional Reserves in Stroke". Stroke 2012, 43(9), E92-E92.
• Jakovljevic DG, Popadic-Gacesa JZ, Barak OF, Nunan D, Donovan G, Trenell MI, Grujic NG, Brodie DA. Relationship between peak cardiac pumping capability and indices of cardio-respiratory fitness in healthy individuals. Clinical Physiology and Functional Imaging 2012, 32(5), 388-393.
• Jakovljevic DG, Moore S, Hallsworth K, Fattakhova G, Thoma C, Trenell MI. Comparison of cardiac output determined by bioimpedance and bioreactance methods at rest and during exercise. Journal of Clinical Monitoring and Computing 2012, 26(2), 63-68.
• Jakovljevic DG, Seferovic PM, Nunan D, Donovan GC, Trenell MI, Grocott-Mason R, Brodie DA. Reproducibility of cardiac power output and other cardiopulmonary exercise indices in patients with chronic heart failure. Clinical Science 2011, 122(4), 175-181.
• Jakovljevic DG, Birks EJ, George RS, Trenell MI, Seferovic PM, Yacoub MH, Brodie DA. Relationship between peak cardiac pumping capability and selected exercise-derived prognostic indicators in patients treated with left ventricular assist devices. European Journal of Heart Failure 2011, 13(9), 992-999.
• Jones DEJ, Hollingsworth KG, Jakovljevic DG, Fattakhova G, Pairman J, Blamire AM, Trenell MI. Loss of capacity to recover from acidosis on repeat exercise in chronic fatigue syndrome: A case control study. European Journal of Clinical Investigation 2012, 42(2), 186-194.
• Barak OF, Ovcin ZB, Jakovljevic DG, Lozanov-Crvenkovic Z, Brodie DA, Grujic NG. Heart rate recovery after submaximal exercise in four different recovery protocols in male athletes and non-athletes. Journal of Sports Science and Medicine 2011, 10(2), 369-375.
• Gacesa J, Jakovljevic D, Kozic D, Dragnic N, Brodie D, Grujic N. Morpho-functional response of the elbow extensor muscles to twelve-week self-perceived maximal resistance training. Clinical Physiology and Functional Imaging 2010, 30(6), 413-419.
• Jakovljevic DG, George RS, Nunan D, Donovan G, Bougard RS, Yacoub MH, Birks EJ, Brodie DA. The impact of acute reduction of continuous-flow left ventricular assist device support on cardiac and exercise performance. Heart 2010, 96(17), 1390-1395.
• Jakovljevic DG, George RS, Donovan G, Nunan D, Henderson K, Bougard RS, Yacoub MH, Birks EJ, Brodie DA. Comparison of cardiac power output and exercise performance in patients with left ventricular assist devices, explanted (recovered) patients and those with moderate to severe heart failure . The American Journal of Cardiology 2010, 105(12), 1780-1785.
• Jakovljevic DG, Donovan G, Nunan D, McDonagh S, Trenell MI, Grocott-Mason R, Brodie DA. The effect of aerobic versus resistance exercise training on peak cardiac power output and physical functional capacity in patients with chronic heart failure. International Journal of Cardiology 2010, 145(3), 526-528.
• Nunan D, Jakovljevic DG, Donovan G, Singleton LD, Sandercock GRH, Brodie DA. Resting autonomic modulations and the heart rate response to exercise. Clinical Autonomic Research 2010, 20(4), 213-221.
• Hagget A, Hull J, Nunan D, Jakovljevic DG, Brodie DA, Amsley L. Application of bioreactance for cardiac output assessment in healthy individuals. European Journal of Applied Physiology 2010, 109(5), 945-951.
• Barak OF, Jakovljevic DG, Popadic-Gacesa JZ, Brodie DA, Grujic NG. Comparison of heart rate variability before and after cycle exercise in relation to different body positions. Journal of Sport Science and Medicine 2010, 9, 176-182.
• Ostojic SM, Markovic G, Calleja-Gonzalez J, Jakovljevic DG, Vucetic V, Stojanovic MD. Ultra short-term heart rate recovery after maximal exercise in continuous versus intermittent endurance athletes. European Journal of Applied Physiology 2010, 108(5), 1055-1059.
• Nunan D, Donovan G, Jakovljevic DG, Hodges LD, Sandercock GR, Brodie DA. Validity and reliability of short-term heart-rate variability from the Polar S810. Medicine and Science in Sports and Exercise 2009, 41(1), 243-250.
• Jakovljevic DG, McConnell AK. Influence of different breathing frequencies on the severity of inspiratory muscle fatigue induced by high-intensity front crawl swimming. Journal of Strength and Conditioning Research 2009, 23(4), 1169-1174.
• Popadic Gacesa JZ, Kozic DB, Dragnic NR, Jakovljevic DG, Brodie DA, Grujic NG. Changes of functional status and volume of triceps brachii measured by magnetic resonance imaging after maximal resistance training. Journal of Magnetic Resonance Imaging 2009, 29(3), 671-676.
• Jakovljevic DG, Nunan D, Donovan G, Hodges LD, Sandercock GR, Brodie DA. Comparison of cardiac output determined by different rebreathing methods at rest and at peak exercise. European Journal of Applied Physiology 2008, 102(5), 593-599.
• Nunan D, Jakovljevic DG, Donovan G, Hodges LD, Sandercock GR, Brodie DA. Levels of agreement for RR intervals and short-term heart rate variability obtained from the Polar S810 and an alternative system. European Journal of Applied Physiology 2008, 103(5), 529-537.
• Jakovljevic DG, Nunan D, Donovan G, Hodges LD, Sandercock GRH, Brodie DA. Lack of agreement between gas exchange variables measured by two metabolic systems. Journal of Sports Science and Medicine 2008, 7(1), 15-22.
• Jones KL, Whittaker RG, Miller JA, Jakovljevic DG, Turnbull DM, Gorman GS. Can high intensity interval training improve functional capacity and clinical symptoms in inflammatory and mitochondrial myopathies?. In: 6th Annual Translational Research Conference. 2013, Oxford, UK.
• Jakovljevic DG, Mc Diarmid A, MacGowan GA, Parry G, Schueler S, Trenell MI. Left Ventricular Assist Device Implantation Significantly Improves Everyday Physical Activity and Quality of Life in Patients with Chronic Heart Failure. In: 32nd Anniversary Meeting of the International Society for Heart and Lung Transplantatio. 2012, Prague, Czech Republic: Elsevier Inc.
• Moore SA, Jakovljevic DG, Ford GA, Rochester L, Trenell MI. The effect of a community exercise intervention on physiological and physical function following stroke: a randomized, controlled trial. In: UK Stroke Forum 2012 Conference. 2012, Harrogate, UK: Wiley-Blackwell Publishing Ltd.
• Bates MGD, Hollingsworth KG, Newman J, Jakovljevic DG, Keavney BD, Blamire AM, MacGowan GA, Chinnery PF, Turnbull DM, Taylor RW, Trenell MI, Gorman GS. Concentric hypertrophic remodelling and subendocardial dysfunction in mitochondrial DNA point mutation carriers. In: Annual Conference of the British Cardiovascular Society (BCS). 2012, Manchester, UK: BMJ Group.
• Newman J, Jakovljevic D, Bates MG, Turnbull DM, Galna B, Trenell MI, Gorman GS. Improving clinical trials evaluation: physiological and functional correlates in mitochondrial disease. In: United Kingdom Neuromuscular Translational Research Conference. 2012, Newcastle upon Tyne, UK: Elsevier Ltd.
• Bates MG, Hollingsworth KG, Newman J, Jakovljevic D, Dixon BJ, Blamire AM, MacGowan GA, Keavney BD, Chinnery PF, Turnbull DM, Taylor RW, Trenell MI, Gorman GS. Evidence of early cardiac impairment in m.3243A > G mutation carriers. In: United Kingdom Neuromuscular Translational Research Conference. 2012, Newcastle upon Tyne, UK: Elsevier Ltd.
• Jakovljevic DG, Papakonstantinou L, Taylor R, MacGowan G, Trenell MI. Every day physical activity protects against the age related decline in aerobic function but not cardiac pumping capability in normoglycemic women. In: Diabetes and Cardiovascular Disease EASD Study Group. 2010, Belgrade, Serbia.
• Jakovljevic DG, Birks EJ, Yacoub MH, Goldspink DF, Tan LB, Brodie DA. Can non-pulsatile continuous-flow left ventricular assist devices confer physiologically desirable cardiac and physical functional benefits during peak exercise?. In: British Cardiovascular Society Annual Conference. 2010, Manchester, UK: Heart.
• Jakovljevic DG, George R, Donovan G, Nunan D, Bougard R, Birks E, Yacoub M, Brodie DA. Resting and exercise haemodynamic and metabolic responses to acute reduction of continuous-flow left ventricular assist device support. European Heart Journal Supplements 2009, 30, 388.
• Donovan G, George R, Jakovljevic DG, Nunan D, Bougard R, Yacoub M, Birks E, Brodie DA. Effects of left ventricular assist devices on heart rate and Vo2 recovery trends following peak exercise: optimal vs reduced unloading speed. European Heart Journal Supplements 2009, 30, 388.
• Nunan D, Jakovljevic DG, Donovan G, Sandercock GRH, Grocott-Mason R, McDonagh S, Brodie DA. Measures of heart rate variability from the Polar S810 and HRV analysis software 1.1: A validity and reliability study in chronic heart failure. In: European Society of Cardiology Congress. 2009, Barcelona, Spain: European Heart Journal, Oxford University Press.
• Jakovljevic DG, Donovan G, Nunan D, GrocottMason R, McDonagh S, Brodie DA. The effect of aerobic versus resistance exercise training on cardiac power output and selected cardio-respiratory variables in patients with stable chronic heart failure. European Journal of Heart Failure 2009, 8(2), 138.
• Donovan G, Nunan D, Jakovljevic DG, Brodie DA. The effects of body positions and gender on heart rate recovery. In: British Association for Sport and Exercise Science Conference. 2009, Leeds Metropolitan University: British Association for Sport and Exercise Science.
• Jakovljevic DG, Donovan G, Nunan D, George R, Bougard R, Birks E, Yacoub M, Brodie DA. Cardiac power output measurements in patients on left ventricular assist devices, explanted (recovered) patients and those with severe heart failure. European Journal of Cardiovascular Prevention & Rehabilitation 2008, 15(s1), 111 no. 487.
• Donovan G, Nunan D, Jakovljevic DG, GrocottMason R, McDonagh S, Brodie DA. Heart rate recovery following either an aerobic or resistance exercise intervention in two participants with chronic heart failure: a case study. In: British Cardiovascular Society, Association for Cardiac Rehabilitation. 2008, York,UK.
• Jakovljevic DG, Donovan G, Nunan D, George R, Bougard R, Birks E, Yacoub M, Brodie DA. Relationship between peak cardiac power output and selected cardio-pulmonary variables in patients on left ventricular assist devices, explanted (recovered) patients and those with severe heart failure. European Journal of Heart Failure 2008, 7(1), 73 no. 287.
• Nunan D, Donovan G, Jakovljevic DG, George R, Bougard R, Birks E, Yacoub M, Brodie DA. Assessing autonomic and cardiac function during ‘bridge-to-recovery’ using left ventricular assist device combination therapy – a case study comparison. In: British Cardiovascular Society, Association for Cardiac Rehabilitation. 2007, Cardiff, Wales.
• Jakovljevic DG, Donovan G, Nunan D, George R, Bougard R, Birks E, Yacoub M, Brodie DA. Current tendencies in cardiopulmonary exercise testing in heart failure – role of cardiac power output. In: Physical Activity and Health. 2007, Belgrade,Serbia: International Council of Sport Science and Physical Education (ICSSPE).
• Jakovljevic DG, Nunan D, Donovan G, Hodges L, Sandercock GRH, Brodie DA. Direct comparison of two automated metabolic gas analysis systems during exercise. In: 12th Annual Congress of the European College of Sports Science. 2007, Jyvaskyla, Finland: European College of Sport Science.
• Nunan D, Jakovljevic DG, Donovan G, Hodges L, Sandercock GRH, Brodie DA. The reliability of the Polar S810 heart rate monitor and advanced analysis software to assess heart rate variability. In: European College of Sport Science. 2007, Jyvaskyla, Finland.
• Jakovljevic D, Nunan D, Donovan G, Hodges L, Sandercock G, Brodie D. Three different rebreathing methods for measuring cardiac output at rest. In: 12th Annual Congress of the European College of Sport Science. 2007, Jyvaskyla, Finland.
• Jakovljevic DG, Nunan D, Donovan G, George RS, Bougard R, Birks EJ, Yacoub MH, Brodie DA. Cardiac power output in patients with severe heart failure, including those with implanted and explanted left ventricular assist devices. In: Thematic Meeting - Clinical Consequences of Haemodynamic Measurements under Exercise Testing. 2007, Copenhagen, Denmark.
• Hodges L, Jakovljevic DG, Brodie DA. The measurement of cardiac power output using a non-invasive rebreathing method. In: Main Meeting of the Physiological Society. 2006, London, England: Physiological Society.
• Jakovljevic DG, McConnell AK. Influence of different breathing frequencies upon inspiratory muscle fatigue induced by high intensity front crawl swimming. In: 10th Annual Congress of the European College of Sport Science. 2005, Belgrade,Serbia: European College of Sport Science.
• Hallsworth K, Hollingsworth KG, Thoma C, Jakovljevic DG, MacGowan GA, Anstee QM, Day CP, Taylor R, Trenell MI. Cardiac function improves following high intensity intermittent exercise in adults with non-alcoholic fatty liver disease. In: Diabetes UK Annual Professional Conference. 2013, Manchester, UK: Diabetes UK.
• Detko E, O'Hara JP, Thelwall PE, Smith FE, Jakovljevic DG, King RFGJ, Trenell MI. Liver and muscle glycogen repletion using C-13 magnetic resonance spectroscopy following ingestion of maltodextrin, galactose, protein and amino acids. British Journal of Nutrition 2013, 110(5), 848-855.
• Jones K, Whittaker R, Miller J, Jakovljevic D, Turnbull D, Gorman G. The Effects of High Intensity Interval Training on Clinical Symptoms and Functional Capacity in Adults with Neuromuscular Disease. In: Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP). 2013, London, UK: BMJ Publishing Group.
• Newman J, Galna B, Jakovljevic D, Bates M, Schaefer A, McFarland R, Turnbull D, Trenell M, Rochester L, Gorman G. Evaluation of Functional Outcome Measures as a Surrogate Marker of Disease Severity in Patients with Mitochondrial Disease. In: Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP). 2013, London, UK: BMJ Publishing Group.
• Hallsworth K, Hollingsworth KG, Thoma C, Jakovljevic D, MacGowan GA, Anstee QM, Day CP, Taylor R, Trenell MI. Cardiac function improves following high intensity intermittent exercise in adults with non-alcoholic fatty liver disease. In: Diabetes UK Professional Conference 2013. 2013, Manchester, UK: Wiley-Blackwell.
• Denton SJ, vanHees VT, Bawamia B, Veerasamy M, Quinn L, Dunford JR, Trenell MI, Jakovljevic DG, Kunadian V. Sedentary Behaviour and Physical Activity Among Older Patients Following Percutaneous Coronary Intervention Presented with Stable Angina versus Acute Coronary Syndrome. In: American Heart Association's 2014 Scientific Sessions and Resuscitation Science Symposium. 2014, Chicago, Illinois: American Heart Association , Inc.
• Cassidy S, Thoma C, Hallsworth K, Parikh J, Hollingsworth KG, Day CP, Jakovljevic DG, Taylor R, Trenell MI. High intensity intermittent training improves cardiac function and reduces liver fat in adults with Type 2 diabetes: an MRI/S study. In: Diabetes UK Professional Conference. 2015, London, UK: Wiley-Blackwell Publishing Ltd.
• Moore S, Hallsworth K, Jakovljevic D, Blamire A, He J, Ford G, Rochester L, Trenell M. Effects of exercise therapy on metabolic risk factors, brain atrophy and cerebral blood flow following stroke: A randomised controlled trial. In: UK Stroke Forum 2014. 2014, Harrogate: Wiley-Blackwell Publishing Asia.
• Campbell MD, Walker M, Trenell MI, Stevenson EJ, Jakovljevic DG, Bracken RM, Bain SC, Turner D, West DJ. The preservation of glycaemia through large pre- and post-exercise rapid-acting insulin reductions prevents early, but not late-onset hypoglycaemia in individuals with Type 1 diabetes. In: Diabetes UK Professional Conference. 2013, Manchester, UK: John Wiley & Sons Ltd.
• Cassidy SA, Thoma C, Hallsworth K, Jakovljevic DG, Parikh J, Hollingsworth KG, Taylor R, Trenell MI. High intensity intermittent exercise reverses abnormal cardiac function in people with type 2 diabetes: an MRI/S study. In: 50th General Assembly of the European Association for the Study of Diabetes. 2014, Vienna, Austria: Springer.
• Charman SJ, Brown E, Okwose NC, Markovic M, Ropret R, Cassidy S, MacGowan GA, Jakovljevic DG. Increased level of habitual physical activity improves body composition and exercise tolerance but has limited effect on cardio-metabolic function in middle-aged women. In: 5th UK Congress on Obesity. 2018, Newcastle upon Tyne, UK.
• Popovic D, Guazzi M, Jakovljevic DG, Lasica R, Banovic M, Ostojic M, Arena R. Quantification of coronary artery disease using different modalities of cardiopulmonary exercise testing. International Journal of Cardiology 2019, 285, 11-13.
• Okwose NC, Cassidy S, Trennel M, Bailey K, Skinner J, MacGowan GA, Jakovljevic DG. Haemodynamic effects of a novel, personalised, home-based physical activity intervention for chronic heart failure. In: Heart Failure 2017: 4th World Congress on Acute Heart Failure. 2017, Paris, France: European Society of Cardiology.
• Parovic M, Okwose NC, Charman SJ, Cassidy S, Doherty P, Bailey K, Skinner J, Seferovic PM, MacGowan GA, Jakovljevic DG. N-terminal prohormone brain natriuretic peptide is a weak indicator of cardiac function and haemodynamic response to exercise in chronic heart failure. In: Heart Failure 2018 & World Congress on Acute Heart Failure. 2018, Vienna, Austria: John Wiley & Sons Ltd.
• Popovic D, Bjelobrk M, Tesic M, Seman S, Jayasinghe S, Hills AP, Babu AS, Jakovljevic DG, Stoner L, Ozemek C, Bond S, Faghy MA, Pronk NP, Lavie CJ, Arena R. Defining the importance of stress reduction in managing cardiovascular disease - the role of exercise. Progress in Cardiovascular Diseases 2022, 70, 84-93.
• Piculin M, Smole T, Zunkovic B, Kokalj E, Robnik-Sikonja M, Kukar M, Fotiadis DI, Pezoulas VC, Tachos NS, Barlocco F, Mazzarotto F, Popovic D, Maier LS, Velicki L, Olivotto I, MacGowan GA, Jakovljevic DG, Filipovic N, Bosnic Z. Disease Progression of Hypertrophic Cardiomyopathy: Modeling Using Machine Learning. JMIR Medical Informatics 2022, 10(2), e30483.
• Preveden A, Golubovic M, Bjelobrk M, Miljkovic T, Ilic A, Stojsic S, Gajic D, Glavaski M, Maier LS, Okwose N, Popovic D, Barlocco F, Ristic A, Macgowan GA, Olivotto I, Filipovic N, Jakovljevic DG, Velicki L. Gender Related Differences in the Clinical Presentation of Hypertrophic Cardiomyopathy—An Analysis from the SILICOFCM Database. Medicina 2022, 58(2), 314.
• Pezoulas VC, Grigoriadis GI, Gkois G, Tachos NS, Smole T, Bosnic Z, Piculin M, Olivotto I, Barlocco F, Robnik-Sikonja M, Jakovljevic DG, Goules A, Tzioufas AG, Fotiadis DI. A computational pipeline for data augmentation towards the improvement of disease classification and risk stratification models: A case study in two clinical domains. Computers in Biology and Medicine 2021, 134, 104520.
• Smole T, Zunkovic B, Piculin M, Kokalj E, Robnik-Sikonja M, Kukar M, Fotiadis DI, Pezoulas VC, Tachos NS, Barlocco F, Mazzarotto F, Popovic D, Maier L, Velicki L, MacGowan GA, Olivotto I, Filipovic N, Jakovljevic DG, Bosnic Z. A machine learning-based risk stratification model for ventricular tachycardia and heart failure in hypertrophic cardiomyopathy. Computers in Biology and Medicine 2021, 135, 104648.
• Harwood AE, Russell S, Okwose NC, McGuire S, Jakovljevic DG, McGregor G. A systematic review of rehabilitation in chronic heart failure: evaluating the reporting of exercise interventions. ESC Heart Failure 2021, 8(5), 3458-3471.
• Wibowo PG, Charman SJ, Okwose NC, Velicki L, Popovic D, Hollingsworth KG, Macgowan GA, Jakovljevic DG. Association between cardiac high-energy phosphate metabolism and whole body metabolism in healthy female adults. Physiological Research 2021, 70(3), 393-399.
• Charman SJ, Velicki L, Okwose NC, Harwood A, McGregor G, Ristic A, Banerjee P, Seferovic PM, MacGowan GA, Jakovljevic DG. Insights into heart failure hospitalizations, management, and services during and beyond COVID-19. ESC Heart Failure 2021, 8(1), 175-182.
• Gerhard EF, Wang L, Singh R, Schueler S, Genovese LD, Woods A, Tang D, Smith NR, Psotka MA, Tovey S, Desai SS, Jakovljevic DG, MacGowan GA, Shah P. LVAD decommissioning for myocardial recovery: Long-term ventricular remodeling and adverse events. Journal of Heart and Lung Transplantation 2021, 40(12), 1560-1570.
• Bouzas-Cruz N, Koshy A, Gonzalez-Fernandez O, Ferrera-Duran C, Green T, Okwose NC, Woods A, Tovey S, Robinson-Smith N, McDiarmid A, Parry G, Gonzalez-Juanatey JR, Schueler S, Jakovljevic DG, MacGowan G. Markers of Right Ventricular Dysfunction Predict Maximal Exercise Capacity after Left Ventricular Assist Device Implantation. ASAIO Journal 2021, 67(3), 284-289.
• Pandhita BAW, Okwose NC, Koshy A, Fernandez OG, Cruz NB, Eggett C, Velicki L, Popovic D, MacGowan GA, Jakovljevic DG. Noninvasive Assessment of Cardiac Output in Advanced Heart Failure and Heart Transplant Candidates Using the Bioreactance Method. Journal of Cardiothoracic and Vascular Anesthesia 2021, 35(6), 1776-1781.
• Mirza KK, Szymanski MK, Schmidt T, de Jonge N, Brahmbhatt DH, Billia F, Hsu S, MacGowan GA, Jakovljevic DG, Agostoni P, Trombara F, Jorde U, Rochlani Y, Vandersmissen K, Reiss N, Russell SD, Meyns B, Gustafsson F. Prognostic Value of Peak Oxygen Uptake in Patients Supported with Left Ventricular Assist Devices (PRO-VAD). Journal of the American College of Cardiology Heart Failure 2021, 9(10), 758-767.
• Fuller A, Okwose N, Scragg J, Eggett C, Luke P, Bandali A, Velicki R, Greaves L, MacGowan GA, Jakovljevic DG. The effect of age on mechanisms of exercise tolerance: Reduced arteriovenous oxygen difference causes lower oxygen consumption in older people. Experimental Gerontology 2021, 149, 111340.
• Okwose NC, Bouzas-Cruz N, Fernandez OG, Koshy A, Green T, Woods A, Robinson-Smith N, Tovey S, Mcdiarmid A, Parry G, Schueler S, Macgowan GA, Jakovljevic DG. Validity of Hemodynamic Monitoring Using Inert Gas Rebreathing Method in Patients With Chronic Heart Failure and Those Implanted With a Left Ventricular Assist Device. Journal of Cardiac Failure 2021, 27(4), 414-418.
• Sengupta SP, Mungulmare K, Okwose NC, MacGowan GA, Jakovljevic DG. Comparison of cardiac output estimates by echocardiography and bioreactance at rest and peak dobutamine stress test in heart failure patients with preserved ejection fraction. Echocardiography 2020, 37(10), 1603-1609.
• Tafelmeier M, Baessler A, Wagner S, Unsoeld B, Preveden A, Barlocco F, Tomberli A, Popovic D, Brennan P, MacGowan GA, Ristic A, Velicki L, Olivotto I, Jakovljevic DG, Maier LS. Design of the SILICOFCM study: Effect of sacubitril/valsartan vs lifestyle intervention on functional capacity in patients with hypertrophic cardiomyopathy. Clinical Cardiology 2020, 43(5), 430-440.
• Bouzas-Cruz N, Gonzalez-Fernandez O, Koshy A, Okwose N, Woods A, Robinson-Smith N, Tovey S, McDiarmid A, Parry G, Schueler S, Jakovljevic D, MacGowan G. Elevation of Right-Sided Pressures and Right Ventricular Echocardiographic Parameters: Predictors of Exercise Limitation in Patients with Implanted Continuous Flow Left Ventricular Assist Devices. The Journal of Heart and Lung Transplantation 2020, 39(4), S439-S439.
• Velicki L, Jakovljevic DG, Preveden A, Golubovic M, Bjelobrk M, Ilic A, Stojsic S, Barlocco F, Tafelmeier M, Okwose N, Tesic M, Brennan P, Popovic D, Ristic A, MacGowan GA, Filipovic N, Maier LS, Olivotto I. Genetic determinants of clinical phenotype in hypertrophic cardiomyopathy. BMC Cardiovascular Disorders 2020, 20(1), 516.
• Steele H, Gomez-Duran A, Pyle A, Hopton S, Newman J, Stefanetti RJ, Charman SJ, Parikh JD, He L, Viscomi C, Jakovljevic DG, Hollingsworth KG, Robinson AJ, Taylor RW, Bottolo L, Horvath R, Chinnery PF. Metabolic effects of bezafibrate in mitochondrial disease. EMBO Molecular Medicine 2020, 12(3), e11589.
• Popovic D, Djordjevic T, Jakovljevic D, Ristic A, Lasica R, Arena R, Guazzi M. N-Terminal-pro-Brain natriuretic peptide dynamics during effort phenotypes ischemic heart failure and determines prognosis regardless of ejection fraction. Peptides 2020, 129, 170315.
• Okwose NC, O'Brien N, Charman S, Cassidy S, Brodie D, Bailey K, Macgowan GA, Jakovljevic DG, Avery L. Overcoming barriers to engagement and adherence to a home-based physical activity intervention for patients with heart failure: A qualitative focus group study. BMJ Open 2020, 10(9), e036382.
• Popovic D, Arena R, Jakovljevic D, Ristic A, Guazzi M. Ventricular arrhythmias not meeting criteria for terminating cardiopulmonary exercise testing stratify prognosis and disease severity in heart failure of preserved, midrange, and reduced ejection fraction. Clinical Cardiology 2020, 43(7), 698-705.