Staff Profile
Professor Andrew Cant
Hon Clin Prof Paediatric Immunology
- Email: [email protected]
- Fax: 0191 2820497
- Address: Clinical Resource Building
Level 4 Block 2
Royal Victoria Infirmary
Newcastle upon Tyne
NE1 4LP
A Consultant in Newcastle since 1990, I set up one of two national referral centres for the treatment of children with severe immunological disorders and I am a world leader in the field of childhood infection, immune disorders, and bone marrow transplantation, also holding clinics in Leeds, Scotland and Ireland. My research in these areas has secured over £7 million in grants, and over 150 scientific papers. I am a past President of the European Society for Paediatric Infectious Diseases and President Elect of the European Society for Immunodeficiencies. Despite being a very busy full-time NHS clinician, I was awarded a Personal Chair in 2004 for outstanding research arising from a highly regarded clinical service. I teach at postgraduate events worldwide.
My special interests include severe and unusual infection, tuberculosis, immunodeficiency, auto-immunity and allergy. I am a Trustee of the Bubble Foundation UK , a local charity that has raised over £3 million since 1994 to support the Children's Bone Marrow Transplant Unit’s work and research; successfully pump priming research posts that now have university or NIHR funding.
At national level, I am a key government advisor for the development of general and specialist paediatric services and training. I was the leader of the national review of paediatric specialist services for the UK in 2007, the head of the national training committee for paediatric infectious diseases, immunology and allergy, and I am now a member of the reviewer board of the Royal College of Paediatrics and Child Health (RCPCH).
I am an eminent advocate for primary immunodeficiency internationally, now heading the European Society for Immunodeficiency (ESID) as president after I contributed to the organization for many years in different roles, including chairing the education and BMT working parties. I am also a member of the medical advisory board for the International Patient Organization for Primary Immunodeficiency (IPOPI), and also served as president of the European Society of Paediatric Infectious Diseases (ESPID) previously. I consider myself a strong proponent for primary immunodeficiency awareness and I have contributed to the development of services in many countries, most notably Jordan, Malaysia, Australia and New Zealand.
- Tholouli E, Sturgess K, Dickinson RE, Gennery A, Cant AJ, Jackson G, Lordan J, Hambleton S, Slatter MA, Bigley V, Collin M. In vivo T-depleted reduced intensity transplantation for GATA2-related immune dysfunction. Blood 2018, 131(12), 1383-1387.
- Maccari ME, Abolhassani H, Aghamohammadi A, Aiuti A, Aleinikova O, Bangs C, Baris S, Barzaghi F, Baxendale H, Buckland M, Burns SO, Cancrini C, Cant A, Cathebras P, Cavazzana M, Chandra A, Conti F, Coulter T, Devlin LA, Edgar JDM, Faust S, Fischer A, Prat MG, Hammarstrom L, Heeg M, Jolles S, Karakoc-Aydiner E, Kindle G, Kiykim A, Kumararatne D, Grimbacher B, Longhurst H, Mahlaoui N, Milota T, Moreira F, Moshous D, Mukhina A, Neth O, Neven B, Nieters A, Olbrich P, Ozen A, Schmid JP, Picard C, Prader S, Rae W, Reichenbach J, Rusch S, Savic S, Scarselli A, Scheible R, Sediva A, Sharapova SO, Shcherbina A, Slatter M, Soler-Palacin P, Stanislas A, Suarez F, Tucci F, Uhlmann A, Montfrans J, Warnatz K, Williams AP, Wood P, Kracker S, Condliffe AM, Ehl S. Disease evolution and response to rapamycin in activated phosphoinositide 3-kinase δ syndrome: The European society for immunodeficiencies-activated phosphoinositide 3-kinase δ syndrome registry. Frontiers in Immunology 2018, 9, 543.
- Altmann T, Slack J, Slatter MA, O'Brien C, Cant A, Thomas M, Brodlie M, Annavarapu S, Gennery AR. Endothelial cell damage in idiopathic pneumonia syndrome. Bone Marrow Transplantation 2018, 53(4), 515-518.
- Nademi Z, Wynn RF, Slatter M, Hughes SM, Bonney D, Qasim W, Latour S, Truck J, Patel S, Abinun M, Flood T, Hambleton S, Cant AJ, Gennery AR, Arkwright PD. Hematopoietic stem cell transplantation for cytidine triphosphate synthase 1 (CTPS1) deficiency. Bone Marrow Transplantation 2019, 54(1), 130-133.
- Unni MNM, Elfeky R, Rao K, Nademi Z, Chiesa R, Amrolia P, Skinner R, Slater O, Worth A, Flood T, Abinun M, Hambleton S, Qasim W, Gaspar HB, Cant AJ, Gennery AR, Veys P, Slatter MA. Non-posttransplant lymphoproliferative disorder malignancy after hematopoietic stem cell transplantation in patients with primary immunodeficiency: UK experience. Journal of Allergy and Clinical Immunology 2018, 141(6), 2319-2321.e1.
- Schwab C, Gabrysch A, Olbrich P, Patiño V, Warnatz K, Wolff D, Hoshino A, Kobayashi M, Imai K, Takagi M, Dybedal I, Haddock JA, Sansom D, Lucena JM, Seidl M, SchmittGräff A, Reiser V, Emmerich F, Frede N, Bulashevska A, Salzer U, Schubert D, Hayakawa S, Okada S, Kanariou M, Kucuk ZY, Chapdelaine H, Petruzelkova L, Sumnik Z, Sediva A, Slatter M, Arkwright PD, Cant A, Lorenz H-M, Giese T, Lougaris V, Plebani A, Price C, Sullivan KE, Moutschen M, Litzman J, Freiberger T, vandeVeerdonk FL, Recher M, Albert MH, Hauck F, Seneviratne S, Schmid JP, Kolios A, Unglik G, Klemann C, Speckmann C, Ehl S, Leichtner A, Blumberg R, Franke A, Snapper S, Zeissig S, Cunningham-Rundles C, Giulino-Roth L, Elemento O, Dückers G, Niehues T, Fronkova E, Kanderová V, Platt CD, Chou J, Chatila T, Geha R, McDermott E, Bunn S, Kurzai M, Schulz A, Alsina L, Casals F, Deyà-Martinez A, Hambleton S, Kanegane H, Taskén K, Neth O, Grimbacher B. Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects. Journal of Allergy and Clinical Immunology 2018, 142(6), 1932-1946.
- Shah RM, Elfeky R, Nademi Z, Qasim W, Amrolia P, Chiesa R, Rao K, Lucchini G, Silva JMF, Worth A, Barge D, Ryan D, Conn J, Cant AJ, Skinner R, Abd Hamid IJ, Flood T, Abinun M, Hambleton S, Gennery AR, Veys P, Slatter M. T-cell receptor αβ+ and CD19+ cell-depleted haploidentical and mismatched hematopoietic stem cell transplantation in primary immune deficiency. Journal of Allergy and Clinical Immunology 2018, 141(4), 1417-1426.e1.
- Slatter MA, Rao K, Abd Hamid IJ, Nademi Z, Chiesa R, Elfeky R, Pearce MS, Amrolia P, Worth A, Flood T, Abinun M, Hambleton S, Qasim W, Gaspar HB, Cant AJ, Gennery AR, Veys P. Treosulfan and Fludarabine Conditioning for Hematopoietic Stem Cell Transplantation in Children with Primary Immunodeficiency: UK Experience. Biology of Blood and Marrow Transplantation 2018, 24(3), 529-536.
- Schwerd T, Twigg SRF, Aschenbrenner D, Manrique S, Miller KA, Taylor IB, Capitani M, McGowan SJ, Sweeney E, Weber A, Chen L, Bowness P, Riordan A, Cant A, Freeman AF, Milner JD, Holland SM, Frede N, Müller M, Schmidt-Arras D, Grimbacher B, Wall SA, Jones EY, Wilkie AOM, Uhlig HH. A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis. Journal of Experimental Medicine 2017, 214(9), 2547-2562.
- Battersby AC, Cant AJ. Advances in primary immunodeficiencies. Paediatrics and Child Health 2017, 27(3), 116-120.
- Mahlaoui N, Warnatz K, Jones A, Workman S, Cant A. Advances in the Care of Primary Immunodeficiencies (PIDs): from Birth to Adulthood. Journal of Clinical Immunology 2017, 37(5), 452-460.
- Eapen M, Wang T, Veys PA, Boelens JJ, Martin AS, Spellman S, Bonfim CS, Brady C, Cant AJ, Dalle J-H, Davies SM, Freeman J, Hsu KC, Fleischhauer K, Kenzey C, Kurtzberg J, Michel G, Orchard PJ, Paviglianiti A, Rocha V, Veneris MR, Volt F, Wynn R, Lee SJ, Horowitz MM, Gluckman E, Ruggeri A. Allele-level HLA matching for umbilical cord blood transplantation for non-malignant diseases in children: A retrospective analysis. The Lancet Haematology 2017, 4(7), e325-e333.
- Bigley V, Maisuria S, Cytlak U, Jardine L, Care MA, Green K, Gunawan M, Milne P, Dickinson R, Wiscombe S, Parry D, Doffinger R, Laurence A, Fonseca C, Stoevesandt O, Gennery A, Cant A, Tooze R, Simpson AJ, Hambleton S, Savic S, Doody G, Collin M. Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation. Journal of Allergy and Clinical Immunology 2018, 141(6), 2234-2248.
- Mace EM, Bigley V, Gunesch JT, Chinn IK, Angelo LS, Care MA, Maisuria S, Keller MD, Togi S, Watkin LB, LaRosa DF, Jhangiani SN, Muzny DM, Stray-Pedersen A, Akdemir ZC, Smith JB, Hernandez-Sanabria M, Le DT, Hogg GD, Cao TN, Freud AG, Szymanski EP, Savic S, Collin M, Cant AJ, Gibbs RA, Holland SM, Caligiuri MA, Ozato K, Paust S, Doody GM, Lupski JR, Orange JS. Biallelic mutations in IRF8 impair human NK cell maturation and function. Journal of Clinical Investigation 2017, 127(1), 306-320.
- Coulter TI, Chandra A, Bacon CM, Babar J, Curtis J, Screaton N, Goodlad JR, Farmer G, Steele CL, Leahy TR, Doffinger R, Baxendale H, Bernatoniene J, Edgar JDM, Longhurst HJ, Ehl S, Speckmann C, Grimbacher B, Sediva A, Milota T, Faust SN, Williams AP, Hayman G, Kucuk ZY, Hague R, French P, Brooker R, Forsyth P, Herriot R, Cancrini C, Palma P, Ariganello P, Conlon N, Feighery C, Gavin PJ, Jones A, Imai K, Ibrahim MAA, Markelj G, Abinun M, Rieux-Laucat F, Latour S, Pellier I, Fischer A, Touzot F, Casanova J-L, Durandy A, Burns SO, Savic S, Kumararatne DS, Moshous D, Kracker S, Vanhaesebroeck B, Okkenhaug K, Picard C, Nejentsev S, Condliffe AM, Cant AJ. Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study. Journal of Allergy and Clinical Immunology 2017, 139(2), 597-606.e4.
- Duncan CJA, Dinnigan E, Theobald R, Grainger A, Skelton AJ, Hussain R, Willet JDP, Swan DJ, Coxhead J, Thomas MF, Thomas J, Zamvar V, Slatter MA, Cant AJ, Engelhardt KR, Hambleton S. Early-onset autoimmune disease due to a heterozygous loss-of-function mutation in TNFAIP3 (A20). Annals of the Rheumatic Diseases 2018, 77(5), 783-786.
- Engelhardt KR, Xu Y, Grainger A, Germani Batacchi MGC, Swan DJ, Willet JDP, Abd Hamid IJ, Agyeman P, Barge D, Bibi S, Jenkins L, Flood TJ, Abinun M, Slatter MA, Gennery AR, Cant AJ, Santibanez Koref M, Gilmour K, Hambleton S. Identification of Heterozygous Single- and Multi-exon Deletions in IL7R by Whole Exome Sequencing. Journal of Clinical Immunology 2017, 37(1), 42-50.
- Coulter T, Chandra A, Nejentsev S, Okkenhaug K, Babar J, Bacon CM, Cant AJ, Condliffe AM. Activated PI3-kinase Delta Syndrome (APDS): Genetics, Immunodeficiency, Diagnosis and Related Pathology. In: 205th Meeting of the Pathological Society of Great Britain & Ireland. 2016, London, UK: John Wiley & Sons Ltd.
- Flinn AM, Cant A, Leahy TR, Butler KM, Gennery AR. Autosomal Dominant Hyper IgE Syndrome - Treatment Strategies and Clinical Outcomes. Journal of Clinical Immunology 2016, 36(2), 107-109.
- Gao Y, Arkwright PD, Carter R, Cazaly A, Harrison RJ, Mant A, Cant AJ, Gadola S, Elliott TJ, Khakoo SI, Williams AP. Bone marrow transplantation for MHC class I deficiency corrects T-cell immunity but dissociates natural killer cell repertoire formation from function. Journal of Allergy and Clinical Immunology 2016, 138(6), 1733-1736.e2.
- Singh Dang T, Willet JDP, Griffin HR, Morgan NV, O'Boyle G, Arkwright PD, Hughes SM, Abinun M, Tee LJ, Barge D, Engelhardt KR, Jackson M, Cant AJ, Maher ER, Santibanez Koref M, Reynard LN, Ali S, Hambleton S. Defective Leukocyte Adhesion and Chemotaxis Contributes to Combined Immunodeficiency in Humans with Autosomal Recessive MST1 Deficiency. Journal of Clinical Immunology 2016, 36(2), 117-122.
- Dang TS, Willet JDP, Griffin HR, Morgan NV, O'Boyle G, Arkwright PD, Hughes SM, Abinun M, Tee LJ, Barge D, Engelhardt KR, Jackson M, Cant AJ, Maher ER, Koref MS, Reynard LN, Ali S, Hambleton S. Erratum to: Defective Leukocyte Adhesion and Chemotaxis Contributes to Combined Immunodeficiency in Humans with Autosomal Recessive MST1 Deficiency (vol 36, pg 117, 2016). Journal of Clinical Immunology 2016, 36(3), 336-337.
- Boztug H, Sykora K-W, Slatter M, Zecca M, Veys P, Lankester A, Cant A, Skinner R, Wachowiak J, Glogova E, Pötschger U, Peters C. European Society for Blood and Marrow Transplantation Analysis of Treosulfan Conditioning Before Hematopoietic Stem Cell Transplantation in Children and Adolescents With Hematological Malignancies. Pediatric Blood & Cancer 2016, 63(1), 139-148.
- Slatter M, Nademi Z, Leahy TR, Morillo-Gutierrez B, Dunn J, Barge D, Skinner R, Ryan C, Hambleton S, Abinun M, Flood T, Cant A, Gennery A. Haploidentical CD3 TCRαβ and CD19-depleted second stem cell transplant for steroid-resistant acute skin graft versus host disease. Journal of Allergy and Clinical Immunology 2016, 138(2), 603-605.
- Nademi Z, Slatter MA, Dvorak CC, Neven B, Fischer A, Suarez F, Booth C, Rao K, Laberko A, Rodina J, Bertrand Y, Koltan S, Debski R, Flood T, Abinun M, Gennery AR, Hambleton S, Ehl S, Cant AJ. Hematopoietic stem cell transplant in patients with activated PI3K delta syndrome. Journal of Allergy and Clinical Immunology 2016, 139(6), 1046-1049.
- Slatter MA, Engelhardt KR, Burroughs LM, Arkwright PD, Nademi Z, Skoda-Smith S, Hagin D, Kennedy A, Barge D, Flood T, Abinun M, Wynn RF, Gennery AR, Cant AJ, Sansom D, Hambleton S, Torgerson TR. Hematopoietic stem cell transplantation for CTLA4 deficiency. Journal of ALlergy and Clinical Immunology 2016, 138(2), 615-619.
- Tsilifis C, Gennery AR, Cant A. Presenting features and platelet anomalies in WAS: one centre’s experience. Journal of Clinical Immunology 2016, 36(4), 354-356.
- Bryan BA, Battersby A, Shillitoe BMJ, Barge D, Bourne H, Flood T, Cant AJ, Stroud C, Gennery AR. Respiratory Health and Related Quality of Life in Patients with Congenital Agammaglobulinemia in the Northern Region of the UK. Journal of Clinical Immunology 2016, 36(5), 472-479.
- Savic S, Parry D, Carter C, Johnson C, Logan C, Gutierrez BM, Thomas JE, Bacon CM, Cant A, Hambleton S. A new case of Fas-associated death domain protein deficiency and update on treatment outcomes. Journal of Allergy and Clinical Immunology 2015, 136(2), 502-505.
- Robertson N, Engelhardt K, Morgan N, Barge D, Cant A, Hugues S, Abinun M, Xu YB, Koref M, Arkwright P, Hambleton S. A Novel 10bp Frameshift Deletion In ICOS In Two Patients With Combined Immunodeficiency. In: UK PIN 2015. 2015, Belfast, Northern Ireland: Wiley-Blackwell Publishing Ltd.
- Speckmann C, Doerken S, Aiuti A, Albert MH, Al-Herz W, Allende LM, Scarselli A, Avcin T, Perez-Becker R, Cancrini C, Cant A, Di Cesare S, Finocchi A, Fischer A, Gaspar HB, Ghosh S, Gennery A, Gilmour K, Gonzalez-Granado LI, Martinez-Gallo M, Hambleton S, Hauck F, Hoenig M, Moshous D, Neven B, Niehues T, Notarangelo L, Picard C, Rieber N, Schulz A, Schwarz K, Seidel MG, Soler-Palacin P, Stepensky P, Strahm B, Vraetz T, Warnatz K, Winterhalter C, Worth A, Fuchs S, Uhlmann A, Ehl S. A prospective study on the natural history of patients with profound combined immunodeficiency: An interim analysis. Journal of Allergy and Clinical Immunology 2015, 139(4), 1302-1310.e4.
- Coulter T, Chandra A, Bacon CM, Babar J, Curtis J, Farmer G, Steele CL, Leahy TR, Doffinger R, Baxendale H, Bernatoniene J, Edgar JDM, Longhurst HJ, Ehl S, Speckmann C, Grimbacher B, Sediva A, Faust SN, Williams AP, Hayman G, Kucuk ZY, Brooker R, Forsyth P, Herriot R, Cancrini C, Palma P, Ariganello P, Feighery C, Gavin PJ, Jones A, Ibrahim MAA, Markelj G, Abinun M, Touzot F, Rieux-Laucat F, Latour S, Moshous D, Pellier I, Fischer A, Casanova JL, Durandy A, Burns SO, Savic S, Kumararatne DS, Kracker S, Vanhaesebroeck B, Okkenhaug K, Picard C, Nejentsev S, Condliffe AM, Cant AJ. Activated PI3-Kinase Delta Syndrome: Clinical, Radiological And Laboratory Features Of A Large Cohort. In: UKPIN 2015 Meeting. 2015, Belfast, Northern Ireland: Wiley-Blackwell Publishing Ltd.
- Robertson N, Engelhardt KR, Morgan NV, Barge D, Cant AJ, Hughes SM, Abinun M, Xu YB, Koref MS, Arkwright PD, Hambleton S. Astute Clinician Report: A Novel 10 bp Frameshift Deletion in Exon 2 of ICOS Causes a Combined Immunodeficiency Associated with an Enteritis and Hepatitis. Journal of Clinical Immunology 2015, 35(7), 598-603.
- Al Qayoodhi A, Hambleton S, Hattersley AT, Cant AJ, Flanagan SE, Engelhardt K, Swan D, Willet J, Xu YB, Koref MS, Leahy TR. Autoimmunity In STAT3 Gain Of Function Mutations; Broadening The Phenotype. In: UKPIN 2015 Meeting. 2015, Belfast, Northern Ireland: Wiley-Blackwell Publishing Ltd.
- Milner JD, Vogel TP, Forbes L, Ma CA, Stray-Pedersen A, Niemela JE, Lyons JJ, Engelhardt KR, Zhang Y, Topcagic N, Roberson EDO, Matthews H, Verbsky JW, Dasu T, Vargas-Hernandez A, Varghese N, McClain KL, Karam LB, Nahmod K, Makedonas G, Mace EM, Sorte HS, Perminow G, Rao VK, O'Connell MP, Price S, Su HC, Butrick M, McElwee J, Hughes JD, Willet J, Swan D, Xu Y, Santibanez-Koref M, Slowik V, Dinwiddie DL, Ciaccio CE, Saunders CJ, Septer S, Kingsmore SF, White AJ, Cant AJ, Hambleton S, Cooper MA. Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations. Blood 2015, 125(4), 591-599.
- Boztug H, Glogova E, Potschger U, Zecca M, Veys P, Lankester A, Cant A, Skinner R, Slatter M, Wachowiak J, Sykora KW, Peters C, EBMT Pediatric Dis Working Party. EBMT metaanalysis of treosulfan conditioning before allogeneic hematopoietic stem cell transplantation in paediatric patients with haematological malignancies. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation. 2015, Istanbul, Turkey: Nature Publishing Group.
- Gambineri E, Mannurita SC, Robertson H, Vignoli M, Haugk B, Lionetti P, Hambleton S, Barge D, Gennery AR, Slatter M, Nademi Z, Flood TJ, Jackson A, Abinun M, Cant AJ. Gut immune reconstitution in immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome after hematopoietic stem cell transplantation. Journal of Allergy and Clinical Immunology 2015, 135(1), 260-262.e8.
- Morillo-Gutierrez B, Nademi Z, Dunn J, Barge D, Hambleton S, Abinun M, Flood T, Cant AJ, Gennery A, Slatter M. Haploidentical TCRab and CD19 Depleted Stem Cell Transplant for Primary Immunodeficiency-6 cases. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation. 2015, Istanbul, Turkey: Nature Publishing Group.
- Duncan CJA, Mohamad SMB, Young DF, Skelton AJ, Leahy TR, Munday DC, Butler KM, Morfopoulou S, Brown JR, Hubank M, Connell J, Gavin PJ, McMahon C, Dempsey E, Lynch NE, Jacques TS, Valappil M, Cant AJ, Breuer J, Engelhardt KR, Randall RE, Hambleton S. Human IFNAR2 deficiency: lessons for antiviral immunity. Science Translational Medicine 2015, 7(307), 307ra154.
- Duncan C, Mohamad S, Young D, Skelton A, Leahy R, Munday D, Butler K, Morfopoulou S, Brown J, Hubank M, Connell J, Gavin P, McMahon C, Dempsey E, Lynch N, Jacques T, Valappil M, Cant A, Engelhardt K, Breuer J, Randall R, Hambleton S. Human IFNAR2 Deficiency: Lessons For Antiviral Immunity. In: UKPIN 2015 Meeting. 2015, Belfast, Northern Ireland: Wiley-Blackwell Publishing Ltd.
- Engelhardt KR, Xu YB, Grainger A, Batacchi MGCG, Swan DJ, Willet JDP, Abd Hamid IJ, Agyeman P, Barge D, Bibi S, Jenkins L, Flood T, Abinun M, Slatter M, Gennery AR, Cant AJ, Koref MS, Hambleton S. Identification Of Heterozygous Single- And Multi-exon Deletions In IL7R By Whole Exome Sequencing. In: UKPIN 2015 Meeting. 2015, Belfast, Northern Ireland: Wiley-Blackwell Publishing Ltd.
- Wehr C, Gennery AR, Lindemans C, Schulz A, Hoenig M, Marks R, Recher M, Gruhn B, Holbro A, Heijnen I, Meyer D, Grigoleit G, Einsele H, Baumann U, Witte T, Sykora K-W, Goldacker S, Regairaz L, Aksoylar S, Ardeniz O, Zecca M, Zdziarski P, Meyts I, Matthes-Martin S, Imai K, Kamae C, Fielding A, Seneviratne S, Mahlaoui N, Slatter MA, Gungor T, Arkwright PD, Van Montfrans J, Sullivan KE, Grimbacher B, Cant A, Peter H-H, Finke J, Gaspar HB, Warnatz K, Rizzi M. Multicenter experience in hematopoietic stem cell transplantation for serious complications of common variable immunodeficiency. Journal of Allergy and Clinical Immunology 2015, 135(4), 988-997.e6.
- Abinun M, Lilic D, Devlin L, Christie S, Edgar D, Depner M, Fuchs S, Grimbacher B, Cant A, Flood T, Hambleton S, Gennery A, Nademi Z, Slatter M. Successful Allogeneic Haematopoietic Stem Cell Transplantation In A Child With Severe Immunodeficiency 31-C (OMIM # 614162) Due To STAT1-GOF Mutation. In: UKPIN 2015. 2015, Wiley-Blackwell.
- Engelhardt KR, Gertz ME, Keles S, Schaffer AA, Sigmund EC, Glocker C, Saghafi S, Pourpak Z, Ceja R, Sassi A, Graham LE, Massaad MJ, Mellouli F, Ben-Mustapha I, Khemiri M, Kilic SS, Etzioni A, Freeman AF, Thiel J, Schulze I, Al-Herz W, Metin A, Sanal O, Tezcan I, Yeganeh M, Niehues T, Dueckers G, Weinspach S, Patiroglu T, Unal E, Dasouki M, Yilmaz M, Genel F, Aytekin C, Kutukculer N, Somer A, Kilic M, Reisli I, Camcioglu Y, Gennery AR, Cant AJ, Jones A, Gaspar BH, Arkwright PD, Pietrogrande MC, Baz Z, Al-Tamemi S, Lougaris V, Lefranc G, Megarbane A, Boutros J, Galal N, Bejaoui M, Barbouche MR, Geha RS, Chatila TA, Grimbacher B. The extended clinical phenotype of 64 patients with dedicator of cytokinesis 8 deficiency. Journal of Allergy and Clinical Immunology 2015, 136(2), 402-412.
- Reda SM, Cant AJ. The importance of vaccination and immunoglobulin treatment for patients with primary immunodeficiency diseases (PIDs) - World PI Week April 22-29, 2015. European Journal of Immunology 2015, 45(5), 1285-1286.
- Reda SM, Cant AJ. The importance of vaccination and immunoglobulin treatment for patients with primary immunodeficiency diseases La importancia de la vacunación y el tratamiento con inmunoglobulina para pacientes con inmunodeficiencias primarias. Acta Pediatrica de Mexico 2015, 36(2), 55-57.
- Rensing-Ehl A, Volkl S, Speckmann C, Lorenz MR, Ritter J, Janda A, Abinun M, Pircher H, Bengsch B, Thimme R, Fuchs I, Ammann S, Allgauer A, Kentouche K, Cant A, Hambleton S, da Cunha CB, Huetker S, Kuhnle I, Pekrun A, Seidel MG, Hummel M, Mackensen A, Schwarz K, Ehl S. Abnormally differentiated CD4+ or CD8+ T cells with phenotypic and genetic features of double negative T cells in human Fas deficiency. Blood 2014, 124(6), 851-860.
- Worth AJJ, Nademi Z, Kammermeier J, Bunn S, Chiesa R, Cant A, Hambleton S, Shah N, Slatter M, Rao K, Gennery A, Elawad M, Amrolia P, Veys P. Allogeneic Stem Cell Transplant Offers Cure for Intractable Childhood Enteropathy. In: 2014 BMT Tandem Meetings. 2014, Dallas, Texas: Elsevier Inc.
- Kharya G, Nademi Z, Leahy T, Brigham K, Barge D, Hambleton S, Abinun M, Flood T, Cant A, Slatter M, Gennery A. Common Gamma chain- and JAK3-deficient SCID, conditioned versus unconditioned transplant: a single centre experience. In: 40th Annual Meeting of the European Group for Blood and Marrow Transplantation. 2014, Milan, Italy: Nature Publishing Group.
- Lu W, Zhang Y, McDonald DO, Jing HE, Carroll B, Robertson N, Zhang Q, Griffin H, Sanderson S, Lakey JH, Morgan NV, Reynard LN, Zheng L, Murdock HM, Turvey SE, Hackett SJ, Prestidge T, Hall JM, Cant AJ, Matthews HF, Koref MFS, Simon AK, Korolchuk VI, Lenardo MJ, Hambleton S, Su HC. Dual Proteolytic Pathways Govern Glycolysis and Immune Competence. Cell 2014, 159(7), 1578-1590.
- Frans G, Moens L, Schaballie H, Van Eyck L, Borgers H, Wuyts M, Dillaerts D, Vermeulen E, Dooley J, Grimbacher B, Cant A, Declerck D, Peumans M, Renard M, De Boeck K, Hoffman I, Francois I, Liston A, Claessens F, Bossuyt X, Meyts I. Gain-of-function mutations in signal transducer and activator of transcription 1 (STAT1): Chronic mucocutaneous candidiasis accompanied by enamel defects and delayed dental shedding. Journal of Allergy and Clinical Immunology 2014, 134(5), 1209-1213.
- Abinun M, Nademi Z, Flood TJ, Friswell M, Foster HE, Hambleton S, Gennery AR, Cant AJ, Slatter M. Haematopoietic stem cell transplantation (hsct) for severe autoimmune and autoinflammatory syndromes in children. In: 100th J Project Meeting. 2014, Antalya, TURKEY: Springer.
- Elfeky R, Nademi Z, Brigham K, Barge D, Hambleton S, Abinun M, Flood T, Cant A, Slatter M, Gennery A. Haematopoietic stem cell transplantation for RAG1/2 severe combined immunodeficiency or Omenn syndrome: a single centre experience. In: 40th Annual Meeting of the European Group for Blood and Marrow Transplantation. 2014, Milan, Italy: Nature Publishing Group.
- Kharya G, Nademi Z, Leahy TR, Dunn J, Barge D, Schulz A, Cant A, Gennery A, Slatter M. Haploidentical T-cell alpha beta receptor and CD19-depleted stem cell transplant for Wiskott-Aldrich syndrome. Journal of Allergy and Clinical Immunology 2014, 134(5), 1199-1201.
- Morillo-Gutierrez B, Nademi Z, Dunn J, Barge D, Hambleton S, Abinum M, Flood T, Cant AJ, Gennery AR, Slatter M. Haploidentical TCR Alfa/Beta and CD19 Depleted Stem Cell Transplant for Primary Immunodeficiency-4 Cases. In: European Society for Immunodeficiencies. 2014, Prague, Czech Republic: Springer.
- Bigley V, Dickinson R, Jardine L, Milne PPS, Griffin H, Santibanez-Koref M, Haniffa M, Cant A, Hambleton S, Gennery A, Collin M. Human SHP-1 Mutation Causes an Autoinflammatory and Immunodeficiency Phenotype. In: European Society for Immunodeficiencies. 2014, Prague, Czech Republic: Springer.
- Mannurita SC, Vignoli M, Colarusso G, Bacchetta R, Cecconi M, Tommasini A, Gennery A, Holland SM, Cant AJ, Gambineri E. Inherited Multiple Autoimmunity: Molecular and Clinical Characterization of IPEX and IPEX-Like Syndromes. In: European Society for Immunodeficiencies. 2014, Prague, Czech Republic: Springer.
- Mannurita SC, Vignoli M, Bacchetta R, Cecconi M, Tommasini A, Gennery AR, Cant AJ, Gambineri E. IPEX and 'IPEX-Like' Syndrome: FOXP3 and Related Pathway. In: 2014 CIS Annual Meeting: Primary Immune Deficiency Diseases North American Conference. 2014, Baltimore, MD: Springer US.
- Lane JR, Evans PTG, Nademi Z, Barge D, Jackson A, Hambleton S, Flood TJ, Cant AJ, Abinun M, Slatter MA, Gennery AR. Low-Dose Serotherapy Improves Early Immune Reconstitution after Cord Blood Transplantation for Primary Immunodeficiencies. Biology of Blood and Marrow Transplantation 2014, 20(2), 243-249.
- Parry DA, Maisuria S, Argumugacani G, Logan CV, Wood PM, Cant A, Gooi HC, Johnson CA, Nejentsev S, Doody G, Savic S. Mutation of Phosphoinositide-3-Kinase Regulatory Subunit Alpha 1, Leading to Hyperactivation of Phosphoinositide-3-Kinase, Results in an Immunodeficiency Resembling APDS. In: 16th Biennial Meeting of the European Society for Immunodeficiences (ESID 2014). 2014, Prague, Czech Republic: Springer.
- Griffith LM, Cowan MJ, Notarangelo LD, Kohn DB, Puck JM, Pai SY, Ballard B, Bauer SC, Bleesing JJH, Boyle M, Brower A, Buckley RH, van der Burg M, Burroughs LM, Candotti F, Cant AJ, Chatila T, Cunningham-Rundles C, Dinauer MC, Dvorak CC, Filipovich AH, Fleisher TA, Gaspar HB, Gungor T, Haddad E, Hovermale E, Huang F, Hurley A, Hurley M, Iyengar S, Kang EM, Logan BR, Long-Boyle JR, Malech HL, McGhee SA, Modell F, Modell V, Ochs HD, O'Reilly RJ, Parkman R, Rawlings DJ, Routes JM, Shearer WT, Small TN, Smith H, Sullivan KE, Szabolcs P, Thrasher A, Torgerson TR, Veys P, Weinberg K, Zuniga-Pflucker JC, Workshop Participants. Primary Immune Deficiency Treatment Consortium (PIDTC) report. Journal of Allergy and Clinical Immunology 2014, 133(2), 335-347.
- Nademi Z, Slatter M, Gambineri E, Mannurita SC, Barge D, Hodges S, Bunn S, Thomas J, Haugk B, Hambleton S, Flood T, Cant A, Abinun M, Gennery A. Single centre experience of haematopoietic SCT for patients with immunodysregulation, polyendocrinopathy, enteropathy, X-linked syndrome. Bone Marrow Transplantation 2014, 49(2), 310-312.
- Flinn A, Abinun M, Leahy R, Cant A, Butler K, Gennery AR. STAT3-Deficient Hyper Ige Syndrome in a Pediatric Cohort. In: 2014 CIS Annual Meeting: Primary Immune Deficiency Diseases North American Conference. 2014, Baltimore, MD: Springer.
- Coulter TI, Chandra A, Leahy TR, Curtis J, Bacon CM, Babar J, Farmer G, Savic S, Burns SO, Jones AM, Gavin PJ, Feighery CF, Forsyth P, Herriot R, Edgar JD, Abinun M, Markelj G, Ibrahim M, Baxendale H, Doffinger R, Kumararatne D, Condliffe AM, Cant AJ, Nejentsev S. The Clinical Manifestations, Management and Outcomes of Activated PI3K-Delta Syndrome (APDS) in UK and Ireland Cohort. In: European Society for Immunodeficiencies. 2014, Prague, Czech Republic: Springer.
- Engelhardt KR, Gertz EM, Schaffer AA, Keles S, Sigmund EC, Ceja R, Sassi A, Graham L, Masaad MJ, Mellouli F, Ben-Mustapha I, Khemiri M, Kilic SS, Etzioni A, Freeman AF, Thiel J, Schulze I, Al-Herz W, Metin A, Sanal O, Tezcan I, Yeganeh M, Niehues T, Dueckers G, Weinspach S, Patiroglu T, Unal E, Dasouki M, Yilamaz M, Genel F, Aytekin C, Kutukculer N, Somer A, Kilic M, Reisli I, Camcioglu Y, Gennery AR, Cant AJ, Jones A, Gaspar HB, Arkwright PD, Pietrogrande MC, Baz Z, Al-Tamemi S, Lougaris V, Lefranc G, Megarbane A, Boutros J, Galal N, Bejaoui M, Barbouche MR, Geha RS, Chatila TA, Grimbacher B. The Extended Clinical Phenotype of 58 Patients with Dock8 Deficiency. In: European Society for Immunodeficiencies. 2014, Prague, Czech Republic: Springer.
- Abinun M, Cant A, Strain L, Lilic D. Treatment Options for Severe Immunodeficiency Due to Gain-of-Function STAT-1 Mutation. In: ESID Meeting. 2014, Prague, Czech Republic: Springer.
- Cole T, Pearce MS, Cant AJ, Cale CM, Goldblatt D, Gennery AR. Clinical outcome in children with chronic granulomatous disease managed conservatively or with hematopoietic stem cell transplantation. Journal of Allergy and Clinical Immunology 2013, 132(5), 1150-1155.
- Cole TS, McKendrick F, Cant AJ, Pearce MS, Cale CM, Goldblatt DR, Gennery AR, Titman P. Cognitive Ability in Children with Chronic Granulomatous Disease: A Comparison of Those Managed Conservatively with Those Who Have Undergone Hematopoietic Stem Cell Transplant. Neuropediatrics 2013, 44(4), 230-232.
- Slatter M, Nademi Z, Patel S, Barge D, Valappil M, Brigham K, Hambleton S, Clark J, Flood T, Cant A, Abinun M, Gennery A. Haploidentical hematopoietic stem cell transplantation can lead to viral clearance in severe combined immunodeficiency. Journal of Allergy and Clinical Immunology 2013, 131(6), 1705-1708.e1.
- Cole T, McKendrick F, Titman P, Cant AJ, Pearce MS, Cale CM, Goldblatt D, Gennery AR. Health Related Quality of Life and Emotional Health in Children with Chronic Granulomatous Disease: A Comparison of Those Managed Conservatively with Those That Have Undergone Haematopoietic Stem Cell Transplant. Journal of Clinical Immunology 2013, 33(1), 8-13.
- Angulo I, Vadas O, Garcon F, Banham-Hall E, Plagnol V, Leahy TR, Baxendale H, Coulter T, Curtis J, Wu CX, Blake-Palmer K, Perisic O, Smyth D, Maes M, Fiddler C, Juss J, Cilliers D, Markelj G, Chandra A, Farmer G, Kielkowska A, Clark J, Kracker S, Debre M, Picard C, Pellier I, Jabado N, Morris JA, Barcenas-Morales G, Fischer A, Stephens L, Hawkins P, Barrett JC, Abinun M, Clatworthy M, Durandy A, Doffinger R, Chilvers ER, Cant AJ, Kumararatne D, Okkenhaug K, Williams RL, Condliffe A, Nejentsev S. Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage. Science 2013, 342(6160), 866-871.
- Rensing-Ehl A, Janda A, Lorenz MR, Gladstone BP, Fuchs I, Abinun M, Albert M, Butler K, Cant A, Cseh AM, Ebinger M, Goldacker S, Hambleton S, Hebart H, Houet L, Kentouche K, Kuhnle I, Lehmberg K, Mejstrikova E, Niemeyer C, Minkov M, Neth O, Duckers G, Owens S, Rosler J, Schilling FH, Schuster V, Seidel MG, Smisek P, Sukova M, Svec P, Wiesel T, Gathmann B, Schwarz K, Vach W, Ehl S, Speckmann C. Sequential decisions on FAS sequencing guided by biomarkers in patients with lymphoproliferation and autoimmune cytopenia. Haematologica 2013, 98(12), 1948-1955.
- Hambleton S, Goodbourn S, Young DF, Dickinson P, Mohamad SMB, Valappil M, McGovern N, Cant AJ, Hackett SJ, Ghazal P, Morgan NV, Randall RE. STAT2 deficiency and susceptibility to viral illness in humans. Proceedings of the National Academy of Sciences of the United States of America 2013, 110(8), 3053-3058.
- Cant A, Battersby A. When to Think of Immunodeficiency?. Hot Topics in Infection and Immunity in Children IX 2013, 764, 167-177.
- Hambleton S, McDonald DO, Morgan NV, Griffin H, Singh-Dang T, Grainger A, Reynard L, Gennery AR, Slatter M, Flood TJ, McKiernan P, Barge D, Abinun M, Hackett S, Loughlin J, Lakey J, Cant AJ, Santibanez-Koref M. Autosomal recessive combines immunodeficiency due to loss of function mutation in Tripeptidyl Peptidase II. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
- Barge D, Bainbridge M, Slatter M, Gennery A, Hambleton S, Abinun M, Flood T, Cant A, Spickett G. Class switch memory B cells in assessing humoral immunity post HSCT for primary immune deficiency. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
- Colarusso G, Mannurita SC, Vignoli M, Barzaghi F, Passerini L, Cancrini C, Cant A, Gennery A, Abinun M, Ikinciogullari A, Lionetti P, Bacchetta R, Gambineri E. Clinical analysis of the complex world of inherited multiple autoimmunity. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
- Engelhardt KR, Gertz EM, Keles S, Schaffer AA, Ceja R, Sassi A, Massaad MJ, Mellouli F, Benmustapha I, Khemiri M, Kilic SS, Etzioni A, Freeman AF, Thiel J, Schulze I, Al-Herz W, Metin A, Sanal O, Yeganeh M, Niehues T, Siepermann K, Unal E, Patiroglu T, Dasouki M, Yilmaz M, Genel F, Aytekin C, Kutukculer N, Somer A, Kilic M, Reisli I, Camcioglu Y, Gennery AR, Cant AJ, Jones A, Gaspar HB, Arkwright PD, Pietrogrande MC, Baz Z, Al-Tamemi S, Lougaris V, Lefranc G, Megarbane A, Boutros J, Galal N, Bejaoui M, Barbouche R, Geha RS, Chatila TA, Grimbacher B. Dock8 deficiency and a diagnostic score to differentiate it from other hyper-IgE syndromes. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
- Cole TS, Jones LKR, McGrogan P, Pearce MS, Flood TJ, Cant AJ, Goldblatt D, Thrasher AJ, Gennery AR, McKendrick F, Titman P. Emotional and behavioural difficulties in chronic granulomatous disease. Archives of Disease in Childhood 2012, 97(1), 87-87.
- Mannurita SC, Robertson H, Vignoli M, Hambleton S, Gennery AR, Slatter M, Nademi Z, Barge D, Abinun M, Cant AW, Gambineri E. Gut immune reconstitution in Ipex Syndrome after HSCT. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer New York LLC.
- Gambineri E, Mannurita SC, Robertson H, Vignoli M, Hambleton S, Gennery A, Slatter M, Nademi Z, Barge D, Abinun M, Cant AJ. Gut Immune Reconstitution in IPEX Syndrome After HSCT. In: Annual Meeting of the Clinical Immunology Society (CIS). 2012, Chicago, Illinois, USA: Springer.
- Bigley V, Dickinson R, Gennery A, Griffin H, Haniffa M, McGovern N, Milne P, Cant A, Santibanez-Koref M, Hambleton S, Collin M. Human dendritic cell deficiency. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
- Moreira D, Slatter M, Nademi Z, Brigham K, Barge D, Jackson A, Flood T, Cant A, Abinun M, Hambleton S, Gennery A. Immune reconstitution and clinical outcome after HSCT infusion for severe combined immunodeficiency in Newcastle. In: Biology of Blood and Marrow Transplantation: BMT Tandem Meeting. 2012, San Diego, California, USA: Elsevier Inc.
- Esteves I, Badawy S, Nademi Z, Barge D, Hambleton S, Flood T, Cant AJ, Abinun M, Slatter M, Gennery AR. Immunological reconstitution after haematopoietic stem cell transplantation for CD40L deficiency. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
- Cole TS, Johnstone IC, Pearce MS, Fulton B, Cant AJ, Gennery AR, Slatter MA. Outcome of children requiring intensive care following haematopoietic SCT for primary immunodeficiency and other non-malignant disorders. Bone Marrow Transplantation 2012, 47(1), 40-45.
- Lane J, Slatter M, Nademi Z, Tierney P, Barge D, Hambleton S, Flood T, Cant A, Abinun M, Jackson G, Collin M, Gennery A. Outcome of haematopoietic stem cell transplantation in patients with chronic granulomatous disease at a national centre. In: 38th Annual Meeting of the European Group for Blood and Marrow Transplantation (EBMT). 2012, Geneva, Switzerland: Nature Publishing Group.
- Maggina P, Nademi Z, Barge D, Hambleton S, Flood T, Cant AJ, Abinun M, Slatter M, Gennery A. Outcome of haematopoietic stem cell transplantation in patients with major histocompatibility class II deficiency at a national centre. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
- Cole T, McKendrick F, Titman P, Cant AJ, Pearce MS, Cale CM, Goldblatt D, Gennery AR. Quality of life and emotional functioning in children with chronic granulomatous disease. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
- Sturgess K, Slatter M, Bigley V, Dickinson R, Haniffa M, McGovern N, Jardine L, Jackson G, Cant A, Gennery A, Hambleton S, Collin M. Reduced-intensity haematopoietic stem cell transplant rescues immune function and corrects pulmonary alveolar proteinosis in DCML deficiency/GATA 2 mutation. In: 38th Annual Meeting of the European Group for Blood and Marrow Transplantation (EBMT). 2012, Geneva, Switzerland: Nature Publishing Group.
- Hambleton S, Goodbourn S, Young DF, Mohamad SMB, Valappil M, Cant AJ, Hackett S, Morgan NV, Randall RE. STAT2 deficiency and susceptibility to viral illness in humans. In: European Congress of Immunology. 2012, Glasgow, UK: Wiley-Blackwell.
- Hambleton S, Goodbourn S, Young D, Mohamad SMB, Cant AJ, Hackett S, Valappil M, Dickenson P, Morgan NV, Ghazal P, Randall RE. STAT2 deficiency causes susceptibility to viral illness in humans. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
- O'Sullivan MD, Cant AJ. The 10 warning signs: a time for a change?. Current Opinion in Allergy and Clinical Immunology 2012, 12(6), 588-594.
- Slatter M, Rao K, Krol L, Sedlacek P, Nademi Z, Chiesa R, Amrolia P, Flood T, Abinun M, Cant A, Hambleton S, Gaspar H, Veys P, Gennery A. Treosulfan, fludarabine and alemtuzumab conditioning for haematopoietic stem cell transplantation in children with chronic granulomatous disease: experience in three centres. In: 38th Annual Meeting of the European Group for Blood and Marrow Transplantation (EBMT). 2012, Geneva, Switzerland: Nature Publishing Group.
- Rensing-Ehl A, Janda A, Vach W, Gladstone BP, Abinun M, Albert MH, Butler K, Cant A, Cseh A, Ebinger M, Goldacker S, Hambleton S, Hebart H, Houet L, Kentouche K, Kuhnle I, Lehmberg K, Mejstrikova E, Niemeyer C, Minkov M, Neth O, Dueckers G, Owens S, Richards M, Rosler J, Schilling FH, Schuster V, Seidel MG, Smisek P, Sukova M, Svec P, Wiesel T, Lorenz M, Schwarz K, Ehl S, Speckmann C. When should the FAS gene be sequenced in patients with lymphoproliferation and autoimmunity. In: 15th Biennial Meeting of the European Society for Immunodeficiencies. 2012, Florence, Italy: Springer.
- Griffin H, McDonald DO, Singh-Dang T, Dickinson R, Grainger A, Reynard L, Hussain R, Cant AJ, Gennery AR, Abinun M, Flood TJ, Collin MP, Loughlin J, Morgan NV, Santibanez-Koref M, Hambleton S. Whole exome sequencing as a diagnostic tool in primary immunodeficiency. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
- Hambleton S, Salem S, Bustamente J, Bigley V, Boisson-Dupuis S, Azevedo J, Fortin A, Haniffa M, Ceron-Gutierrez C, Bacon CM, Menon G, Trouillet C, McDonald D, Carey P, Ginhoux F, Alsina L, Zumwalt TJ, Kong X, Kumararatne D, Butler K, Hubeau M, Feinberg J, Al-Muhsen S, Cant A, Abel L, Chaussabel D, Doffinger R, Talesnik E, Grumach A, Duarte A, Abarca K, Moraes-Vasconcelos D, Burk D, Berghuis A, Geissmann F, Collin M, Casanova J-L, Gros P. IRF8 Mutations and Human Dendritic-Cell Immunodeficiency. New England Journal of Medicine 2011, 365(2), 127-138.
- Subbarayan A, Colarusso G, Hughes SM, Gennery AR, Slatter M, Cant AJ, Arkwright PD. Clinical Features That Identify Children With Primary Immunodeficiency Diseases. Pediatrics 2011, 127(5), 810-816.
- Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern N, Spence L, Pagan S, Carey C, Dimmick I, Chua I, Wallis J, Lordan J, Morgan C, Kumararatne DS, Doffinger R, van der Burg M, van Dongen J, Cant A, Jackson G, Dick JE, Hambleton S, Collin M. Dendritic cell, monocyte, B and NK lymphoid deficiency: a novel but potentially fatal haematological disorder curable with haematopoietic stem cell transplantation. In: Bone Marrow Transplantation: 37th European Group for Bone and Marrow Transplantation. 2011, Paris, France: Nature Publishing Group.
- Evans P, Lane JP, Slatter MA, Barge D, Jackson A, Hambleton S, Flood TJ, Abinun M, Cant AJ, Gennery AR. EFFECT OF SEROTHERAPY DOSE ON IMMUNORECONSTITUTION FOLLOWING UMBILICAL CORD STEM CELL TRANSPLANT FOR PRIMARY IMMUNODEFICIENCY. In: PEDIATRIC RESEARCH. 2011, 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA: NATURE PUBLISHING GROUP.
- Dickinson RE, Griffin H, Bigley V, Reynard LN, Hussain R, Haniffa M, Lakey JH, Rahman T, Wang XN, McGovern N, Pagan S, Cookson S, McDonald D, Chua I, Wallis J, Cant A, Wright M, Keavney B, Chinnery PF, Loughlin J, Hambleton S, Santibanez-Koref M, Collin M. Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency. Blood 2011, 118(10), 2656-2658.
- Siah TW, Cant AJ, Leech SN, Taylor AEM. Gross generalized molluscum contagiosum in a patient with autosomal recessive hyper-IgE syndrome. In: British Society for Paediatric Dermatology 26th Annual Symposium and AGM. 2011, Nottingham, UK: Wiley-Blackwell.
- Slatter MA, Cant AJ. Hematopoietic stem cell transplantation for primary immunodeficiency diseases. In: Casanova, J.L., Conley, M.E., Notarengelo, L, ed. The Year in Human and Medical Genetics: Inborn Errors of Immunity I. Oxford, UK: Wiley-Blackwell, 2011, pp.122-131.
- Lane JP, Evans PTG, Slatter MA, Barge D, Jackson A, Hambleton S, Flood T, Abinun M, Cant J, Gennery A. Immune reconstitution post umbilical cord blood stem cell transplantation for primary immunodeficiency in a national centre. In: Bone Marrow Transplantation: 37th European Group for Bone and Marrow Transplantation. 2011, Paris, France: Nature Publishing Group.
- Moratto D, Giliani S, Bonfim C, Mazzolari E, Fischer A, Ochs HD, Cant AJ, Thrasher AJ, Cowan MJ, Albert MH, Small T, Pai SY, Haddad E, Lisa A, Hambleton S, Slatter M, Cavazzana-Calvo M, Mahlaoui N, Picard C, Torgerson TR, Burroughs L, Koliski A, Zanis-Neto J, Porta F, Qasim W, Veys P, Kavanau K, Hönig M, Schulz A, Friedrich W, Notarangelo LD. Long-term outcome and lineage-specific chimerism in 194 Wiskott-Aldrich Syndrome patients treated by hematopoietic cell transplantation between 1980-2009: an international collaborative study. Blood 2011, 118(6), 1675-1684.
- Morgan NV, Goddard S, Cardno TS, McDonald D, Rahman F, Barge D, Ciupek A, Straatman-Iwanowska A, Pasha S, Guckian M, Anderson G, Huissoon A, Cant A, Tate WP, Hambleton S, Maher ER. Mutation in the TCRα subunit constant gene (TRAC) leads to a human immunodeficiency disorder characterized by a lack of TCRαβ+ T cells. Journal of Clinical Investigation 2011, 121(2), 695-702.
- Brown L, Xu-Bayford J, Allwood Z, Slatter M, Cant A, Davies EG, Veys P, Gennery AR, Gaspar HB. Neonatal diagnosis of severe combined immunodeficiency leads to significantly improved survival outcome: the case for newborn screening. Blood 2011, 117(11), 3243-3246.
- Brown L, Xu-Bayford J, Allwood Z, Slatter M, Cant A, Davies EG, Veys P, Gennery AR, Gaspar HB. Neonatal Diagnosis of Severe Combined Immunodeficiency Leads to Significantly Improved Survival Outcome: The Case for Newborn Screening [editorial comment]. Obstetrical & Gynecological Survey 2011, 66(7), 398-399.
- Slatter MA, Angus B, Windebank K, Taylor A, Meaney C, Lester T, Norbury G, Hambleton S, Abinun M, Flood TJ, Cant AJ, Gennery AR. Polymorphous lymphoproliferative disorder with Hodgkin-like features in common gamma-chain-deficient severe combined immunodeficiency. Journal of Allergy and Clinical Immunology 2011, 127(2), 533-535.
- Sturgess K, Slatter M, Bigley V, Haniffa M, Wang XN, Dickinson R, McGovern N, Jardine L, Pagan S, Chua I, Wallis J, Lordan J, Morgan C, Cant A, Gennery A, Edmondson R, Bacon C, Black F, Kirkham N, Jackson GH, Hambleton S, Collin MP. Reduced Intensity Hematopoietic Stem Cell Transplant Rescues Immune Function and Corrects Pulmonary Alveolar Proteinosis in DCML Deficiency/GATA 2 Mutation. In: Blood: 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH). 2011, San Diego, California, USA: American Society of Hematology.
- Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern N, Jardine L, Pagan S, Dimmick I, Chua I, Wallis J, Lordan J, Morgan C, Kumararatne DS, Doffinger R, van der Burg M, van Dongen J, Cant A, Dick JE, Hambleton S, Collin M. The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency. Journal of Experimental Medicine 2011, 208(2), 227-234.
- Slatter MA, Rao K, Amrolia P, Flood T, Abinun M, Hambleton S, Nademi Z, Goulden N, Davies G, Qasim W, Gaspar HB, Cant A, Gennery AR, Veys P. Treosulfan-based conditioning regimens for hematopoietic stem cell transplantation in children with primary immunodeficiency: United Kingdom experience. Blood 2011, 117(16), 4367-4375.
- Morgan NV, Goddard S, Cardno TS, Rahman F, Crupek A, Straatman-Iwanowska A, Pasha S, Hambleton S, Cant A, Barge D, Gennery A, McDonald D, Anderson G, Huissoon A, Tate WP, Maher ER. A novel human immunodeficiency disorder associated with a mutation in the T cell receptor a subunit constant gene (TRAC). In: Clinical and Experimental Immunology: United Kingdom Primary Immunodeficiency Network Immunology Forum. 2010, Bath, UK: British Society for Immunology.
- Puel A, Natividad A, Chrabieh M, Döffinger R, Barcenas-Morales G, Picard C, Ouachée-Chardin M, Toulon A, Bustamante J, Al-Muhsen S, Arkwright PD, Costigan C, McConnell V, Cant AJ, Abinun M, Polak M, Bougnères PF, Kumararatne D, Blanche S, Fischer AM, Bodemer C, Abel L, Lilic D, Casanova JL. Autoantibodies against IL-17A, IL-17F and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I. Journal of Experimental Medicine 2010, 207(2), 291-297.
- Nademi Z, Slatter M, Gennety A, Flood T, Hambleton S, Clark J, Friswell M, Foster H, Cant A, Abinun M. Autologous (T-cell depleted) or allogeneic haematopoietic stem cell transplantation for treatment of recalcitrant, severe autoimmune/rheumatic disorders in children?. In: 36th Annual Meeting of the European Group for Blood and Marrow Transplantat/9th Meeting of the EBMT Data Management Group/26th Meeting of the EBMT Nurses Group/2nd EBMT Quality Management Meeting. 2010, Vienna, Austria: Bone Marrow Transplantation, Nature Publishing Group.
- Bordon V, Gennery AR, Slatter MA, Vandecruys E, Laureys G, Veys P, Waseem Q, Friedrich W, Wulfraat NM, Scherer F, Cant AJ, Fischer A, Cavazanna-Calvo M, Bredius RGM, Notarangelo LD, Mazzolari E, Neven B, Tayfun G. Clinical and immunologic outcome of patients with cartilage hair hypoplasia after hematopoietic stem cell transplantation. Blood 2010, 116(1), 27-35.
- Rensing-Ehl A, Warnatz K, Fuchs S, Schlesier M, Salzer U, Draeger R, Bondzio I, Joos Y, Janda A, Gomes M, Abinun M, Hambleton S, Cant A, Shackley F, Flood T, Waruiru C, Beutel K, Siepermann K, Dueckers G, Niehues T, Wiesel T, Schuster V, Seidel MG, Minkov M, Sirkia K, Kopp MV, Korhonen M, Schwarz K, Ehl S, Speckmann C. Clinical and immunological overlap between autoimmune lymphoproliferative syndrome and common variable immunodeficiency. Clinical Immunology 2010, 137(3), 357-365.
- Vignoli M, Mannurita SC, Bianchi L, Bacchetta R, Cecconi M, Tommasini A, Abinun M, Gennery A, Hambleton S, Slatter M, Cant A, de Martino M, Gambineri E. Exploring 'IPEX-like Syndrome': What is Beyond FOXP3 Gene?. In: 10th Annual Meeting of the Federation of Clinical Immunology Societies. 2010, Boston, MA: Clinical Immunology, Academic Press.
- Ng WF, von Delwig A, Carmichael AJ, Arkwright PD, Abinun M, Cant AJ, Jolles S, Lilic D. Impaired TH17 responses in patients with chronic mucocutaneous candidiasis with and without autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. Journal of Allergy and Clinical Immunology 2010, 126(5), 1006-1015.
- Daikeler T, Labopin M, Socie G, Faraci M, Rahman FA, Yesilipek A, Arcese W, Meara AO, Sirvent A, Voswinkel J, Verdeguer A, Gandemer V, Schoemans H, Cant AJ, Messina C, Sedlacek P, Vora AJ, Mialou V, Diez JL, Sora F, Jubert C, Herr AL, Ruggeri A, Crotta A, Gluckman E, Farge D, Rocha V. Incidence and Risk Factors for Secondary Autoimmune Diseases (AD) After Cord Blood Transplantation (CBT) Retrospective Analysis on Behalf of Eurocord and the EBMT Autoimmune Diseases Working Party. In: 52nd Annual Meeting of the American Society of Hematology. 2010, Orlando, FL: Blood: American Society of Hematology.
- Woellner C, Gertz EM, Schaffer AA, Lagos M, Perro M, Glocker EO, Pietrogrande MC, Cossu F, Franco JL, Matamoros N, Pietrucha B, Heropolitanska-Pliszka E, Yeganeh M, Moin M, Espanol T, Ehl S, Gennery AR, Abinun M, Breborowicz A, Niehues T, Kilic SS, Junker A, Turvey SE, Plebani A, Sanchez B, Garty BZ, Pignata C, Cancrini C, Litzman J, Sanal O, Baumann U, Bacchetta R, Hsu AP, Davis JN, Hammarstrom L, Davies EG, Eren E, Arkwright PD, Moilanen JS, Viemann D, Khan S, Laszlo M, Cant AJ, Freeman AF, Puck JM, Holland SM, Grimbacher B. Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome. Journal of Allergy and Clinical Immunology 2010, 125(2), 424-432.
- Woellner C, Gertz ME, Schaffer AA, Lagos M, Perro M, Glocker EO, Pietrogrande MC, Cossu F, Franco JL, Matamoros N, Pietrucha B, Heropolitanska-Pliszka E, Yeganch M, Moin M, Espanol T, Ehl S, Gennery AR, Abinun M, Breborowicz A, Niehues T, Kilic SS, Junker A, Turvey SE, Plebani A, Sanchez B, Garty BZ, Pignata C, Cancrini C, Litzman J, Sanal O, Batimann U, Bacchetta R, Hsu AP, Davis JN, Hammarstrom L, Davies GE, Eren E, Arkwright PD, Moilanen JS, Viemann D, Khan S, Marodi L, Cant AJ, Freeman AF, Puck JM, Holland SM, Grimbacher B. Mutations in the signal transducer and activator of transcription 3 (STAT3) and diagnostic guidelines for the Hyper-IgE Syndrome. In: Clinical and Experimental Immunology: United Kingdom Primary Immunodeficiency Network Immunology Forum. 2010, Bath, UK: Wiley-Blackwell Publishing Ltd.
- Nademi Z, Slatter M, Barge D, Hodges S, Bunn S, Thomas J, Harvey H, Hambleton S, Flood T, Cant A, Abinun M, Gennery A. Single-centre experience of haematopoeitic stem cell transplantation for patients with complex autoimmune enteropathies. In: 36th Annual Meeting of the European Group for Blood and Marrow Transplantation/9th Meeting of the EBMT Data Management Group/26th Meeting of the EBMT Nurses Group/2nd EBMT Quality Management Meeting. 2010, Vienna, Austria: Bone Marrow Transplantation, Nature Publishing Group.
- Slatter M, Nademi Z, Patel S, Barge D, Valappil M, Brigham K, Hambleton S, Flood T, Cant A, Abinun M, Gennery A. Transplantation of CD3/CD19 depleted PBSC leading to viral clearance and no graft-versus-host disease in SCID. In: 36th Annual Meeting of the European Group for Blood and Marrow Transplantat/9th Meeting of the EBMT Data Management Group/26th Meeting of the EBMT Nurses Group/2nd EBMT Quality Management Meeting. 2010, Vienna, Austria: Bone Marrow Transplantation, Nature Publishing Group.
- Gennery AR, Slatter MA, Grandin L, Taupin P, Cant AJ, Veys P, Amrolia PJ, Gaspar HB, Davies EG, Friedrich W, Hoenig M, Notarangelo LD, Mazzolari E, Porta F, Bredius RGM, Lankester AC, Wulffraat NM, Seger R, Gungor T, Fasth A, Sedlacek P, Neven B, Blanche S, Fischer A, Cavazzana-Calvo M, Landais P, and Members of the Inborn Errors Working Party. Transplantation of hematopoietic stem cells and long-term survival for primary immunodeficiencies in Europe: Entering a new century, do we do better?. Journal of Allergy and Clinical Immunology 2010, 126(3), 602-610.
- Slatter M, Rao K, Amrolia P, Flood T, Abinun M, Cant A, Hambleton S, Goulden N, Davies G, Qasim W, Gasper HB, Gennery A, Veys P. UK experience of treosulfan-based conditioning regimens in children with primary immunodeficiency. In: 36th Annual Meeting of the European Group for Blood and Marrow Transplantat/9th Meeting of the EBMT Data Management Group/26th Meeting of the EBMT Nurses Group/2nd EBMT Quality Management Meeting. 2010, Vienna, Austria: Bone Marrow Transplantation, Nature Publishing Group.
- Bolze A, Byun M, McDonald D, Morgan NV, Abhyankar A, Premkumar L, Puel A, Bacon CM, Rieux-Laucat F, Pang K, Britland A, Abel L, Cant A, Maher ER, Riedl SJ, Hambleton S, Casanova J-L. Whole-exome-sequencing-based discovery of human FADD deficiency. American Journal of Human Genetics 2010, 87(6), 873-881.
- Abinun M, Flood TJ, Cant AJ, Veys P, Gennery AR, Foster HE, Friswell M, Baildam E, Davidson J, Southwood TR, Livermore P, Wedderburn LR. Autologous T cell depleted haematopoietic stem cell transplantation in children with severe juvenile idiopathic arthritis in the UK (2000-2007). Molecular Immunology 2009, 47(1), 46-51.
- Slatter M, Windebank K, Angus B, Barborie A, Perry A, Lester T, Norbury G, Abinun M, Flood T, Cant A, Gennery A. Malignancy as a presentation of common gamma chain deficient severe combined immunodeficiency. In: Bone Marrow Transplantation: 35th Annual Meeting of the European Group for Blood and Marrow Transplantation. 2009, Goteborg, Sweden: Nature Publishing Group.
- Gennery AR, Cant AJ. New Findings in Primary Immunodeficiency. In: Finn, A., Curtis, N., Pollard, A.J, ed. Hot Topics in Infection and Immunity in Children v. 5. New York, USA: Springer, 2009, pp.79-93.
- Slatter M, Ferguson C, Rogerson E, Yurasova A, Askew P, Flood T, Abinun M, Cant A, Bunn S, Thomas J, Gennery A. Nutritional assessment of children undergoing haematopoietic stem cell transplantation for primary immunodeficiency or severe autoimmune disease. In: Bone Marrow Transplantation: 35th Annual Meeting of the European Group for Blood and Marrow Transplantation. 2009, Goteborg, Sweden: Nature Publishing Group.
- Hong M, Ryan KR, Arkwright P, Gennery A, Costigan C, Denning D, Cant AJ, Abinun M, Young DA, McConnell V, Spickett GP, Swan DC, Gillespie CS, Lilac D, Dominguez M. Pattern recognition receptor expression is not impaired in patients with chronic mucocutanous candidiasis with or without autoimmune polyendocrinopathy candidiasis ectodermal dystrophy. Clinical and Experimental Immunology 2009, 156(1), 40-51.
- Soncini E, Slatter MA, Jones LBKR, Hughes S, Hodges S, Flood TJ, Barge D, Spickett GP, Jackson GH, Collin MP, Abinun M, Cant AJ, Gennery AR. Unrelated donor and HLA-identical sibling haematopoietic stem cell transplantation cure chronic granulomatous disease with good long-term outcome and growth. British Journal of Haematology 2009, 145(1), 73-83.
- Gallimore CI, Lewis D, Taylor C, Cant A, Gennery A, Gray JJ. Chronic excretion of a recombinant norovirus in a child with cartilage hair hypoplasia (CHH). Journal of Clinical Virology 2004, 30(2), 196-204.
- Fenton AC, Berrington JE, Spickett GP, Cant AJ, O'Keeffe M, Matthews JN. Haemaphilus influenzaeType b (Hib) antibody response following pragmatic UK immunisation with mixed regimes of acellular and/or whole cell DTPHib combination vaccines. In: Annual Meeting of the Pediatric Academic Societies. 2004, San Francisco, CA: Pediatric Research: International Pediatric Research Foundation.
- Atherton DJ, Gennery AR, Cant AJ. The Neonate - Cutaneous features of primary immunodeficiency disorders. In: Burns, T., Griffiths, C., Cox, N., Breathnach, S, ed. Rook’s Textbook of Dermatology. Oxford, UK: Wiley-Blackwell, 2004, pp.chapter 14.
- Berrington JE, Fenton AC, Spickett GP, Cant AJ. Haemophilus influenzae type b (Hib) antibody response in significantly preterm UK infants. In: Pediatric Research: Annual Meeting of the Pediatric Academic Society. 2003, Seattle, Washington, USA: Lippincott Williams & Wilkins.
- Cant AJ, Gibb D, Davies EG, Cale C, Gennery AR. Immunodeficiency. In: McIntosh, N., Helms, P., Smyth, R, ed. Forfar and Arneil’s Textbook of Pediatrics. Edinburgh, UK: Churchill Livingston, 2003, pp.chapter 25.
- Driessen GJA, Gerritsen EJA, Fischer A, Fasth A, Hop WCJ, Veys P, Porta F, Cant A, Steward CG, Vossen JM, Uckan D, Friedrich W. Long-term outcome of haematopoietic stem cell transplantation in autosomal recessive osteopetrosis: an EBMT report. Bone Marrow Transplantation 2003, 32(7), 657-663.
- Gennery AR, Barge D, O'Sullivan JJ, Flood TJ, Abinun M, Cant AJ. Antibody deficiency and autoimmunity in 22q11.2 deletion syndrome. Archives of Disease in Childhood 2002, 86(6), 422-425.
- Arkwright PD, Abinun M, Cant AJ. Autoimmunity in human primary immunodeficiency diseases. Blood 2002, 99(8), 2694-2702.
- Krishna MT, Hodges E, Lavender FL, Harris S, Gennery A, Cant A, Gibson B, Wilkie R, Darbyshire P, Smith JL. CD3+CD4-CD8+NK- large granular lymphocytosis with neutropenia and evidence for clonality and T-Cell receptor gene rearrangement: Two pediatric cases. Journal of Pediatric Hematology / Oncology 2002, 24(6), 495-498.
- Gennery AR, Cant AJ. Development of allergy post-bone marrow transplantation. Clinical and Experimental Allergy 2002, 32(12), 1677-1678.
- Clark J, Lakshman R, Galloway A, Cant A. Does cefotaxime eradicate nasopharyngeal carriage of N meningiditis. Archives of Disease in Childhood 2002, 87(5), 449-449.
- Dickinson A, Cant A. Haemopoietic stem-cell transplantation: improving immune reconstitution, avoiding graft-versus-host disease. Lancet 2002, 360(9327), 98-99.
- Macdougall CF, Cant AJ, Colver AF. How dangerous is food allergy in childhood? The incidence of severe and fatal allergic reactions across the UK and Ireland. Archives of Disease in Childhood 2002, 86(4), 236-239.
- Arkwright PD, McDermottt MF, Houten SM, Frenkel J, Waterhan HR, Aganna E, Hammond LJ, Mirakian RM, Tomlin P, Vijaydurai PI, Cant AJ. Hyper IgD syndrome (HIDS) associated with in vitro evidence of defective monocyte TNFRSF1A shedding and partial response to TNF receptor blockade with etanercept. Clinical and Experimental Immunology 2002, 130(3), 484-488.
- Colver A, Macdougall C, Cant A. Incidence of severe and fatal reactions to foods - Reply. Archives of Disease in Childhood 2002, 87(5), 451.
- Hoare S, El-Shazali O, Clark JE, Fay A, Cant AJ. Investigation for complement deficiency following meningococcal disease. Archives of Disease in Childhood 2002, 86(3), 215-217.
- Jones L, Flood TJ, McGrogan P, Morton L, Parker L, Goldblatt D, Thrasher A, Cant AJ. Respiratory disease in Chronic Granulomatous Disease. In: Thorax: Winter Meeting of the British Thoracic Society. 2002, London: BMJ Group.
- Dziembowska M, Fondaneche MC, Vedrenne J, Barbieri G, Wiszniewski W, Picard C, Cant AJ, Steimle V, Charron D, Alca-Loridan C, Fischer A, Lisowska-Grospierre B. Three novel mutations of the CIITA gene in MHC class II-deficient patients with a severe immunodeficiency. Immunogenetics 2002, 53(10-11), 821-829.
- Riordan FAI, Cant AJ. When to do a lumbar puncture. Archives of Disease in Childhood 2002, 87(3), 235-237.
- Gennery AR, Cant AJ. Applied Physiology: Immune Competence. Current Paediatrics 2001, 11(6), 458-464.
- Khawaja K, Gennery AR, Flood TJ, Abinun M, Cant AJ. Bone marrow transplantation for CD40 ligand deficiency: a single centre experience. Archives of Disease in Childhood 2001, 84(6), 508-511.
- Gennery AR, Dickinson AM, Brigham K, Barge D, Spickett GP, Curtis A, Spencer V, Jackson A, Carter V, Palmer P, Flood TJ, Cant AJ, Abinun M. CAMPATH-1M T-cell depleted BMT for SCID: long-term follow-up of 19 children treated 1987-98 in a single center. Cytotherapy 2001, 3(3), 221-232.
- Gennery AR, Dickinson AM, Brigham K, Barge D, Spickett GP, Curtis A, Spencer V, Jackson A, Cavanagh G, Carter V, Palmer P, Flood TJ, Cant AJ, Abinun M. CAMPATH-1M T-cell depleted BMT for SCID: Long-term follow-up of 19 children treated 1987-98 in a single center. Cytotherapy 2001, 3(3), 221-232.
- Gennery AR, Cant AJ, Baldwin CI, Calvert JE. Characterization of the impaired antipneumococcal polysaccharide antibody production in immunosuppressed pediatric patients following cardiac transplantation. Journal of Clinical Immunology 2001, 21(1), 43-50.
- Gennery AJ, Cant A, Forsyth RJ. Development of parainfectious opsoclonus in an infant by a non-humoral immune mechanism. Developmental Medicine and Child Neurology 2001, 43(3), 213-214.
- Gennery AR, Cant AJ. Diagnosis of severe combined immunodeficiency. Journal of Clinical Pathology 2001, 54(3), 191-195.
- Gennery AR, Barge D, Spickett GP, Cant AJ. Lymphocyte subset populations in children with polysaccharide antibody deficiency following cardiac transplantation. Journal of Clinical Immunology 2001, 21(1), 37-42.
- Kane L, Gennery AR, Crooks BNA, Flood TJ, Abinun M, Cant AJ. Neonatal bone marrow transplantation for severe combined immunodeficiency. Archives of Disease in Childhood: Fetal and Neonatal Edition 2001, 85(2), F110-F113.
- Khawaja K, Gennery AR, Abinun M, Flood TJ, Cant AJ. Single Supraregional Centre Experience of Bone Marrow Transplantation for CD40L Deficiency. Archives of Disease in Childhood 2001, 84(6), 508-511.
- Nademi Z, Clark J, Richards CGM, Walshaw D, Cant AJ. The causes of fever in children attending hospital in the North of England. Journal of Infection 2001, 43(4), 221-225.
- Aladangady N, Kinmond S, Cant AJ, Gibson B, Coutts JAP. A preterm baby with Omenn syndrome. European Journal of Pediatrics 2000, 159(9), 657-658.
- Gennery AR, Flood TJ, Abinun M, Cant AJ. Bone marrow transplantation does not correct the hyper IgE syndrome. Bone Marrow Transplantation 2000, 25(12), 1303-1305.
- Saleem MA, Arkwright PD, Davies EG, Cant AJ, Veys PA. Clinical course of patients with major histocompatibility complex class II deficiency. Archives of Disease in Childhood 2000, 83(4), 356-359.
- Drummond P, Clark J, Wheeler J, Galloway A, Freeman R, Cant A. Community acquired pneumonia - a prospective UK study. Archives of Disease in Childhood 2000, 83(5), 408-412.
- Arkwright PD, Rieux-Laucat F, Le Deist F, Stevens RF, Angus B, Cant AJ. Cytomegalovirus infection in infants with autoimmune lymphoproliferative syndrome (ALPS). Clinical and Experimental Immunology 2000, 121(2), 353-357.
- Gennery AR, Cant AJ, Jeggo PA. Immunodeficiency associated with DNA repair defects. Clinical and Experimental Immunology 2000, 121(1), 1-7.
- Srinivasan M, Abinun M, Cant AJ, Tan K, Oakhill A, Steward CG. Malignant infantile osteopetrosis presenting with neonatal hypocalcaemia. Archives of Disease in Childhood: Fetal & Neonatal 2000, 83(1), F21-F23.
- Crooks BNA, Taylor CE, Turner AJL, Osman HKE, Abinun M, Flood TJ, Cant AJ. Respiratory viral infections in primary immune deficiencies: significance and relevance to clinical outcome in a single BMT unit. Bone Marrow Transplantation 2000, 26(10), 1097-1102.
- Gennery AR, Clark JE, Flood TJ, Cant AJ. T-cell-depleted bone marrow transplantation from unrelated donor for [correction of allogeneic sibling for] X-linked hyperimmunoglobulin M syndrome. Journal of Pediatrics 2000, 137(2), 290-290.
- Berrington JE, Flood TJ, Abinun M, Galloway A, Cant AJ. Unsuspected Pneumocystis carinii pneumonia at presentation of severe primary immunodeficiency. Archives of Disease in Childhood 2000, 82(2), 144-147.
- Crooks BNA, Taylor CE, Turner AJL, Abinun M, Flood TJ, Cant AJ. Clinical experience of respiratory viral infections in children undergoing bone marrow transplantation for primary immunodeficiencies. In: Bone Marrow Transplantation. 1999, Nature Publishing Group.
- Peake J, Waugh A, Le Deist F, Priestley A, Rieux-Laucat F, Foray N, Capulas E, Singleton BK, de Villartay JP, Cant A, Malaise EP, Fischer A, Hivroz C, Jeggo PA. Combined immunodeficiency associated with increased apoptosis of lymphocytes and radiosensitivity of fibroblasts. Cancer Research 1999, 59(14), 3454-3460.
- Dodman T, Clark J, Cant AJ. Community acquired pneumonia: review of investigations, aetiology, treatment and outcome for inpatients from a UK centre. European Journal of Pediatrics 1999, 158(12), 1005-1005.
- Newson T, Chippindale AJ, Cant AJ. Computed tomography scan assessment of lung disease in primary immunodeficiencies. European Journal of Pediatrics 1999, 158(1), 29-31.
- Datta HK, Cook DB, Kanan RM, Gennery AR, Cant AJ. Evidence for continuous basal generation of Gc-MAF: Absence in infantile osteopetrosis and restoration after bone marrow transplant. Blood 1999, 93(11), 4026-4027.
- Abinun M, Newson T, Rowe PW, Flood TJ, Cant AJ. Importance of neurological assessment before bone marrow transplantation for osteopetrosis. Archives of Disease in Childhood 1999, 80(3), 273-274.
- Bertrand Y, Landais P, Friedrich W, Gerritsen B, Morgan G, Fasth A, Cavazzana-Calvo M, Porta F, Cant A, Espanol T, Muller S, Veys P, Vossen J, Haddad E, Fischer A. Influence of severe combined immunodeficiency phenotype on the outcome of HLA non-identical, T-cell-depleted bone marrow transplantation - A retrospective European survey from the European Group for Bone Marrow Transplantation and the European Society for Immunodeficiency. Journal of Pediatrics 1999, 134(6), 740-748.