Committee staff
Dr Amanda Robe
Research Project Manager
- Email: [email protected]
- Personal Website: Translational and Clinical Research Institute
- Address: Faculty of Medical Sciences,
Wolfson Building , G20
Medical School
Framlington Place
Newcastle upon Tyne
NE2 4HH
Background
My role as a Project Manager within the Faculty of Medical Sciences is varied, ranging from planning to ensure milestones are met, communication to all stakeholders, supporting clinical trials, financial management, co-ordinating outreach activities such as PPI activities, Sandpit events and ECR events.
As the projects are largely translational, a significant part of the role is liaising between the Trust, University, External parties, and the funder.
I currently support translational grants from MRC, NIHR i4i, BBSRC and have previously supported a CRUK grant.
I have a PhD in Immunobiology, and BSc in Applied Biology. I have gained relevant experience from working in drug development and clinical trials within the Pharmaceutical Industry, UK and US government led projects, and also various Project Management roles within academia.
Publications
- Jones DEJ, Robe A, Palmer J, Kirby JA. Adoptive transfer of self-PDC reactive T-cells into naive mice induces portal tract and bile duct changes characteristic of primary biliary cirrhosis (PBC). In: 41st Annual Meeting of the European Association for the Study of the Liver. 2006, Vienna, Austria: ELSEVIER SCIENCE BV.
- McHugh A, Robe AJ, Palmer JM, Jones DEJ. PDC-E3BP is not a dominant T-cell autoantigen in primary biliary cirrhosis. Liver International 2006, 26(4), 406-413.
- Robe AJ, Kirby JA, Jones DEJ, Palmer JM. A key role for autoreactive B cells in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex in the mouse. Hepatology 2005, 41(5), 1106-1112.
- Robe AJ, Kirby JA, Jones DEJ, Palmer JM. A key role for autoreactive B cells in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex in the mouse. Hepatology 2005, 41(5), 1106-1112.
- Robe AJ, Palmer JM, Kirby JA, Jones DEJ. Breakdown of T-cell tolerance to the primary biliary cirrhosis (PBC) autoantigen pyruvate dehydrogenase complex is a B-cell driven process. In: Gut: Annual Meeting of the British Society of Gastroenterology. 2004, Glasgow, UK: BMJ Group.
- Robe AJ, Palmer J, Kirby J, Jones D. Breakdown of T-cell tolerance to the primary biliary cirrhosis (PBC) autoantigen pyruvate dehydrogenase complex is a B-cell driven process. In: Hepatology: 55th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD). 2004, Boston, Massachusetts, USA: John Wiley & Sons, Inc.
- Palmer JM, Robe AJ, Burt AD, Kirby JA, Jones DEJ. Covalent modification as a mechanism for the breakdown of immune tolerance to pyruvate dehydrogenase complex in the mouse. Hepatology 2004, 39(6), 1583-1592.
- Robe AJ, Palmer JM, Kirby JA, Bassendine MF, Jones DEJ. [abstract] Characterisation of liver infiltrating T-cell antigen specificity in a mouse model of primary biliary cirrhosis (PBC). Gut 2002, 50(s2), A116 abstract no. 428.
- Robe A, Palmer J, Kirby J, Jones D. Characterisation of liver infiltrating T-cell antigen specificity in a mouse model of primary biliary cirrhosis (PBC). In: Journal of Hepatology. 2002, Elsevier BV.
- Jones DEJ, Palmer JM, Robe A, Kirby JA. Oral tolerisation to pyruvate dehydrogenase complex as a potential therapy for primary biliary cirrhosis. Autoimmunity 2002, 35(8), 537-544.
- Jones DE, Robe AJ, Palmer JM, Kirby JA. Exploration of the immunogenicity of the primary biliary cirrhosis autoantigen pyuvate dehydrogenase complex. Hepatology 2001, 34, 730.
- Robe AJ, Palmer JM, Kirby JA, Jones DE. No role for autoreactive antibody in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex, the autoantigen in primary biliary cirrhosis. In: Hepatology. 2001, John Wiley & Sons, Inc.
- Robe A, Palmer JM, Yeaman SJ, Jones DEJ. The E3BP (protein X) component of pyruvate dehydrogenase complex (PDC) is not a T-cell autoantigen in primary biliary cirrhosis (PBC). In: JOURNAL OF HEPATOLOGY. 2000.
- Jones DE, Robe AJ, Palmer JM, Yeaman SJ, Kirby JA. The role played by gender in breakdown of immune tolerance in experimental autoimmune cholangitis: A mouse model of primary biliary cirrhosis. In: HEPATOLOGY. 2000.
- Jones DEJ, Palmer JM, Bennett K, Robe AJ, Yeaman SJ, Robertson H, Bassendine MF, Burt AD, Kirby JA. Investigation of a mechanism for accelerated breakdown of immune tolerance to the primary biliary cirrhosis-associated autoantigen, pyruvate dehydrogenase complex. Laboratory Investigation 2002, 82(2), 211-219.
- Jones DEJ, Palmer JM, Burt AD, Walker C, Robe AJ, Kirby JA. Bacterial motif DNA as an adjuvant for the breakdown of immune self-tolerance to pyruvate dehydrogenase complex. Hepatology 2002, 36(3), 679-686.